A comparison of 64Cu-labeled bi-terminally PEGylated A20FMDV2 peptides targeting integrin ανβ6

• Published in: Oncotarget Vol. 13; no. 1; pp. 360 - 372
• Main Authors: Huynh, Truc T., Sreekumar, Sreeja, Mpoy, Cedric, Rogers, Buck E.
• Format: Journal Article
• Language: English
• Published: Impact Journals LLC 16.02.2022
• Subjects: Research Paper

Expression of epithelial-specific integrin α ν β 6 is up-regulated in various aggressive cancers and serves as a prognostic marker. Integrin-targeted PET imaging probes have been successfully developed and tested in the clinic. Radiotracers based on the peptide A20FMDV2 derived from foot-and-mouth d...