Acetazolamide therapy for hypochloremic metabolic alkalosis in pediatric patients with heart disease

• Published in: American journal of therapeutics Vol. 14; no. 4; p. 331
• Main Authors: Moffett, Brady S, Moffett, Tiffany I, Dickerson, Heather A
• Format: Journal Article
• Language: English
• Published: United States 01.07.2007
• Subjects: Acetazolamide - therapeutic use; Alkalosis - chemically induced; Alkalosis - drug therapy; Blood Chemical Analysis; Carbonic Anhydrase Inhibitors - therapeutic use; Child, Preschool; Chlorides - blood; Diuretics - adverse effects; Diuretics - therapeutic use; Female; Heart Diseases - drug therapy; Humans; Infant; Infant, Newborn; Male; Sodium Bicarbonate - blood

Pediatric patients with heart disease are often treated with high doses of diuretics, which can lead to hypochloremic metabolic alkalosis. There are no data in children regarding the efficacy and safety of acetazolamide to treat hypochloremic metabolic alkalosis. Patients from January 2004 to June 2...