Visible-light-induced C–H alkylation of pyridine derivatives via 1,2-hydrogen atom transfer

• Published in: Catalysis science & technology Vol. 15; no. 13; pp. 3940 - 3945
• Main Authors: Ye, Meiling, Tian, Zeyu, Li, Yuanyuan, Wang, Hang, Huang, Tianle, Yang, Zhongzhen, Wu, Yong
• Format: Journal Article
• Language: English
• Published: Cambridge Royal Society of Chemistry 30.06.2025
• Subjects: Alkylation; Cross coupling; Functional groups; Hydrogen atoms; Pyridines; Radicals

A visible-light-induced radical–radical cross-coupling protocol between hydroxamic acid derivatives and pyridine derivatives for the synthesis of pyridin-2-ylmethanamine derivatives via 1,2-hydrogen atom transfer has been reported. This protocol features metal-free and mild reaction conditions, a br...