The abasic site as a challenge to DNA polymerase
An abasic site in DNA creates a strong block to DNA polymerase and is a mutagenic base lesion. In this study, we present structural and dynamic properties of duplex oligodeoxynucleotides containing G, C and T opposite a model abasic site studied by one and two-dimensional nuclear magnetic resonance...
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Published in | Journal of molecular biology Vol. 213; no. 2; pp. 303 - 314 |
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Main Authors | , , , , |
Format | Journal Article |
Language | English |
Published |
Elsevier Ltd
01.05.1990
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Online Access | Get full text |
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