Magnesium stearate susceptibility of directly compressible materials as an indication of fragmentation properties

In the literature, the susceptibility of a material to magnesium stearate lubrication has been assumed to reflect its fragmentation propensity. In the work described here, it was found that this is not a general rule. The effect of magnesium stearate was shown to be dependent on a number of factors,...

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Published inPowder technology Vol. 54; no. 1; pp. 39 - 44
Main Authors Vromans, H., Bolhuis, G.K., Lerk, C.F.
Format Journal Article
LanguageEnglish
Published Elsevier B.V 1988
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Abstract In the literature, the susceptibility of a material to magnesium stearate lubrication has been assumed to reflect its fragmentation propensity. In the work described here, it was found that this is not a general rule. The effect of magnesium stearate was shown to be dependent on a number of factors, including particle size (surface area), flowability and mechanism of consolidation.
AbstractList In the literature, the susceptibility of a material to magnesium stearate lubrication has been assumed to reflect its fragmentation propensity. In the work described here, it was found that this is not a general rule. The effect of magnesium stearate was shown to be dependent on a number of factors, including particle size (surface area), flowability and mechanism of consolidation.
Author Lerk, C.F.
Vromans, H.
Bolhuis, G.K.
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Cites_doi 10.1016/0378-5173(86)90222-X
10.3109/03639048409038309
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    fullname: Duberg
– volume: 32
  start-page: 39
  year: 1986
  ident: 10.1016/0032-5910(88)80047-0_BIB6
  publication-title: Acta Pharm. Techn.
  contributor:
    fullname: Johansson
– volume: 13
  start-page: 144T
  year: 1961
  ident: 10.1016/0032-5910(88)80047-0_BIB19
  publication-title: J. Pharm. Pharmacol.
  doi: 10.1111/j.2042-7158.1961.tb10506.x
  contributor:
    fullname: Shotton
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Snippet In the literature, the susceptibility of a material to magnesium stearate lubrication has been assumed to reflect its fragmentation propensity. In the work...
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Title Magnesium stearate susceptibility of directly compressible materials as an indication of fragmentation properties
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