Mitochondrial Disorders After 12 Months of Human Immunodeficiency Virus Type 1 Preexposure Prophylaxis Based on Tenofovir Disoproxil Fumarate Plus Emtricitabine in Healthy Adults - Muñoz-Muela, Esperanza; Mejías-Trueba, Marta; Serna-Gallego, Ana; Saborido-Alconchel, Abraham; Fernández-Pérez, Susana; Herrero, Marta; Sotomayor, Cesar; Gutiérrez-Valencia, Alicia; Trujillo-Rodríguez, María; López-Cortés, Luis F (The Journal of infectious diseases, 2025)
Keywords: Adult; Anti-HIV Agents - administration & dosage; Anti-HIV Agents - adverse effects; Anti-HIV Agents - therapeutic use; DNA, Mitochondrial; Emtricitabine - administration & dosage; Emtricitabine - adverse effects; Emtricitabine - therapeutic use; Female; Healthy Volunteers; HIV Infections - prevention & control; HIV-1 - drug effects; Humans; Male; Middle Aged; Mitochondria - drug effects; Mitochondrial Diseases - chemically induced; Oxidative Stress - drug effects; Pre-Exposure Prophylaxis; Prospective Studies; Tenofovir - administration & dosage; Tenofovir - adverse effects; Tenofovir - therapeutic use; Young Adult; mitochondrial toxicity; preexposure prophylaxis; healthy subjects; mitochondrial respiration; nucleos(t)ide reverse transcriptase inhibitors