Fcγ receptor-mediated biological activities of human leukemic cell lines and their modulation by transforming growth factor-β1 and interleukin 6

• Published in: Cytokine (Philadelphia, Pa.) Vol. 5; no. 3; pp. 255 - 263
• Main Authors: Morikawa, Minoru, Harada, Naoki, Nunomura, Yuka, Koike, Tsuneaki, Hashimoto, Seiji, Soma, Gen-ichiro, Yoshida, Takeshi
• Format: Journal Article
• Language: English
• Published: Elsevier Ltd 1993
• Subjects: active oxygen molecules; ADCC; Fcγ receptor; human leukemic cell lines; IL-6; TGF-β1; Fcγ receptor; TGF-β1; active oxygen molecules; human leukemic cell lines; ADCC; IL-6

Previously we reported that transforming growth factor-β1 (TGF-β1) remarkably enhanced the differentiation of human leukemic cell lines, HL-60 and THP-1, in the presence of 1α,25-dihydroxyvitamin D 3 (VD 3) and also that it induced Fc receptor for immunoglobulin G (FcγR), type IIIB, in the presence...