Investigation of chemical substances of terrestrial arthropods

• Published in: Bìologìčnì studìï Vol. 13; no. 1; pp. 129 - 144
• Main Author: Klyuchko, O. M.
• Format: Journal Article
• Language: English
• Published: Львівський національний університет імені Івана Франка 2019
• Subjects: Arthropods’ venoms; receptor antagonists; toxins; transmembrane electric current
• ISSN: 1996-4536; 2311-0783
• DOI: 10.30970/sbi.1301.594

Millions of Arthropods are inhabitants of the Earth and some biochemical products which they produce are valuable for human practice. The aim of this work was to summarize current information about chemical substances produced by Arthropods such as venoms, toxins and some other chemical compounds that may be used in practice. Today such products are obtained and purified using standard biochemical methods. In this article, the information about species of the terrestrial Arthropods – producers of substances acting on the nervous system and used in electrophysiological investigations is presented. Some versions of arthropods’ toxins classification and the table with Araneids toxins and effects they occur are suggested as well. Main attention was paid to some Araneidae venoms and toxins that block synaptic transmission in glutamatergic synapses. A review of chemical composition and some biophysical properties of such venoms and toxins was suggested and their chemical structures namely of toxins from spiders of Nephila family and toxins from A. lobata venom were described. Some biophysical properties of Araneidae venoms and toxins are characterized. Other components of Arthropods’ venoms were also observed. Contemporary applications of such chemical compounds in agriculture and in the environmental monitoring systems were considered as well. The obtained results evidence that the terrestrial Arthropods is a valuable source of chemical compounds for biophysical laboratories and their great potential has to attract more attention of investigators.