Ultrasound Neuromodulation (Low‐Intensity Focused Ultrasound) to Treat Knee Osteoarthritis Pain A Randomized, Observer‐ and Participant‐Masked, Sham‐Controlled, Human‐Subjects Pilot Study

• Published in: Journal of ultrasound in medicine Vol. 44; no. 9; pp. 1713 - 1721
• Main Authors: Ilfeld, Brian M., Cao, Khoa N., Branson, Ruben, Bloom, Philip
• Format: Journal Article
• Language: English
• Published: England John Wiley & Sons, Inc 01.09.2025
• Subjects: Adult; Aged; Case Series; Female; Humans; Male; Middle Aged; Osteoarthritis, Knee - complications; Osteoarthritis, Knee - therapy; Pain Management - methods; Pain Measurement; Pilot Projects; Treatment Outcome; Ultrasonic Therapy - methods; chronic pain; pain management; analgesia

Low‐intensity focused ultrasound is a non‐invasive neuromodulation technique that delivers mechanical forces to a deep location within the body through acoustic pressure waves without affecting tissue between the transducer and focal target. Preliminary studies involving healthy volunteers suggest f...