coiTAD: Detection of Topologically Associating Domains Based on Clustering of Circular Influence Features from Hi-C Data

Topologically associating domains (TADs) are key structural units of the genome, playing a crucial role in gene regulation. TAD boundaries are enriched with specific biological markers and have been linked to genetic diseases, making consistent TAD detection essential. However, accurately identifyin...

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Bibliographic Details
Published inGenes Vol. 15; no. 10; p. 1293
Main Authors Houchens, Drew, Chowdhury, H M A Mohit, Oluwadare, Oluwatosin
Format Journal Article
LanguageEnglish
Published Switzerland MDPI AG 30.09.2024
MDPI
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