Harmol induces autophagy and subsequent apoptosis in U251MG human glioma cells through the downregulation of survivin
Saved in:
Published in | Oncology Reports Vol. 29; no. 4; pp. 1333 - 1342 |
---|---|
Main Authors | , |
Format | Journal Article |
Language | English |
Published |
Spandidos Publications
01.04.2013
|
Subjects | |
Online Access | Get full text |
Cover
Loading…
Author | Akihisa Abe Hiroko Kokuba |
---|---|
Author_xml | – sequence: 1 givenname: AKIHISA surname: ABE fullname: ABE, AKIHISA – sequence: 2 givenname: HIROKO surname: KOKUBA fullname: KOKUBA, HIROKO |
BackLink | https://cir.nii.ac.jp/crid/1872272492913725568$$DView record in CiNii |
BookMark | eNp1kDFPwzAQhS1UJErpxg_wwEhKfI7jeEQVtEggFiqxRU5iJ5YSu9hJUf89ScuEhHS6u-F7T3fvGs2sswqhWxKvaCbgwfkVxISuABK4QHPCBYkgoWQ27jGQiFL2eYWWIZgijhMQmeBijoat9J1rsbHVUKqA5dC7fSPrI5a2wmEogvoalO2x3Lt974IJI4p3wMjbBjdDJy2uW-M6iUvVtgH3jXdD3YxT4cp9W6_qoZW9cRY7Pfr5gzkYe4MutWyDWv7OBdo9P32st9Hr--Zl_fgalUA4REWSCMYKKioqNUlK4LrkBQOdyjQmjAmdEZWNT9M41YlmrBTpCeO6UmPRBbo_-5beheCVzvfedNIfcxLnU2q58_mUWj6lNuLwBy9Nfzq-99K0_4nuziJrzMhPnWQcgEMiQBDKgbE0oz-ZzX5b |
CitedBy_id | crossref_primary_10_2174_1871520618666181029133041 crossref_primary_10_1371_journal_pone_0109630 crossref_primary_10_12677_HJMCe_2024_121009 crossref_primary_10_1038_onc_2015_264 crossref_primary_10_1038_s41531_022_00361_4 crossref_primary_10_3390_molecules28093949 crossref_primary_10_1109_TNB_2015_2499312 crossref_primary_10_3390_cancers16112033 crossref_primary_10_1007_s00044_024_03333_w crossref_primary_10_4155_fmc_2019_0294 crossref_primary_10_1002_ptr_7955 crossref_primary_10_1186_s12985_024_02384_0 crossref_primary_10_1016_j_bmc_2024_118051 crossref_primary_10_1515_psr_2022_0132 crossref_primary_10_1002_slct_201901640 crossref_primary_10_1016_j_phymed_2017_02_008 crossref_primary_10_1002_mc_23482 crossref_primary_10_3390_ijms222312805 crossref_primary_10_1016_j_biopha_2022_112827 crossref_primary_10_1016_j_prp_2024_155285 crossref_primary_10_1186_s13045_022_01350_z crossref_primary_10_2174_0115733947249518231001001728 crossref_primary_10_1016_j_micron_2016_08_009 crossref_primary_10_3892_or_2016_4703 crossref_primary_10_1038_s41467_023_38410_y crossref_primary_10_1177_1721727X221110044 crossref_primary_10_3390_molecules200813941 crossref_primary_10_1016_j_pestbp_2018_12_005 crossref_primary_10_1002_mc_22278 |
Cites_doi | 10.1158/0008-5472.CAN-04-3640 10.1002/1097-0215(20010320)95:2<92::AID-IJC1016>3.0.CO;2-9 10.1126/science.1099993 10.1097/CAD.0b013e32832a2dd9 10.1016/S0092-8674(00)81683-9 10.1200/JCO.1999.17.7.2100 10.1126/science.290.5497.1717 10.1182/blood-2006-07-038059 10.1006/bbrc.1999.1888 10.1016/j.ccr.2006.02.019 10.1038/sj.bjc.6601605 10.1038/onc.2009.519 10.1038/nrd2272 10.2174/092986706779026192 10.1101/gad.13.3.239 10.1159/000136294 10.1016/j.ccr.2007.05.008 10.1158/0008-5472.CAN-05-3557 10.1016/S0376-8716(97)00163-4 10.1073/pnas.79.6.1889 10.1038/25141 10.1021/np030277n 10.1074/jbc.273.50.33533 10.1016/0014-2999(68)90006-X 10.1007/BF00498996 10.1111/j.1742-4658.2010.07965.x 10.1093/emboj/19.21.5720 10.1038/sj.onc.1204264 10.1158/0008-5472.CAN-09-2190 10.1038/nrc2293 10.1007/BF00174615 10.1038/emboj.2009.8 10.1074/jbc.M210998200 10.1016/0006-2952(66)90211-5 10.1093/brain/89.1.37 10.1056/NEJM200101113440207 10.1247/csf.27.431 10.1248/cpb.52.394 10.1016/j.bcp.2011.09.017 10.1038/nrc1560 10.1038/nature06639 10.1074/jbc.274.2.1156 10.1074/jbc.M605488200 10.1006/abbi.1996.9771 10.1016/S1534-5807(04)00099-1 10.1124/jpet.102.047050 10.1016/j.lungcan.2006.06.007 10.1016/0014-4827(78)90533-5 10.1016/0006-2952(58)90025-X 10.4161/auto.1.2.1738 10.1002/jcp.20987 10.1007/BF00498436 10.1172/JCI26390 10.1248/bpb.34.1264 10.4161/auto.3634 10.1021/jf902315e 10.1038/sj.onc.1207521 10.1126/science.290.5497.1761 10.1038/nrmicro865 |
ContentType | Journal Article |
DBID | RYH AAYXX CITATION |
DOI | 10.3892/or.2013.2242 |
DatabaseName | CiNii Complete CrossRef |
DatabaseTitle | CrossRef |
DeliveryMethod | fulltext_linktorsrc |
Discipline | Medicine |
EISSN | 1791-2431 |
EndPage | 1342 |
ExternalDocumentID | 10_3892_or_2013_2242 |
GroupedDBID | --- 0R~ 2WC 53G 7X7 88E 8FI 8FJ ABJNI ABUWG ACGFS ADBBV AEGXH AENEX AFKRA AFOSN AHMBA ALIPV ALMA_UNASSIGNED_HOLDINGS AN0 BAWUL BENPR BNQBC BPHCQ BVXVI CCPQU CS3 DIK E3Z EBS EJD F5P FYUFA GX1 H13 HMCUK HUR HZ~ IAO IHR IPNFZ M1P O9- OK1 PHGZM PHGZT PQQKQ PROAC PSQYO RIG RYH TR2 UKHRP 123 AAYXX ABPMR C45 CITATION EBD EMOBN IHW INH INR ITC ODZKP OGEVE OVD SV3 TEORI UDS |
ID | FETCH-LOGICAL-c2172-b44955b39d3af14c27fc7b52f6a601559f81e8013306f4f55c9614c277fdefde3 |
ISSN | 1021-335X |
IngestDate | Thu Apr 24 23:02:25 EDT 2025 Tue Jul 01 03:06:36 EDT 2025 Fri Jun 27 00:03:21 EDT 2025 |
IsDoiOpenAccess | true |
IsOpenAccess | true |
IsPeerReviewed | false |
IsScholarly | true |
Issue | 4 |
Language | English |
LinkModel | OpenURL |
MergedId | FETCHMERGED-LOGICAL-c2172-b44955b39d3af14c27fc7b52f6a601559f81e8013306f4f55c9614c277fdefde3 |
OpenAccessLink | https://cir.nii.ac.jp/crid/1872272492913725568 |
PageCount | 10 |
ParticipantIDs | crossref_primary_10_3892_or_2013_2242 crossref_citationtrail_10_3892_or_2013_2242 nii_cinii_1872272492913725568 |
ProviderPackageCode | CITATION AAYXX |
PublicationCentury | 2000 |
PublicationDate | 2013-04-00 |
PublicationDateYYYYMMDD | 2013-04-01 |
PublicationDate_xml | – month: 04 year: 2013 text: 2013-04-00 |
PublicationDecade | 2010 |
PublicationTitle | Oncology Reports |
PublicationYear | 2013 |
Publisher | Spandidos Publications |
Publisher_xml | – name: Spandidos Publications |
References | Monzo (key20180107214112_b45-or-29-04-1333) 1999; 17 Altieli (key20180107214112_b48-or-29-04-1333) 2008; 8 Ogier-Denis (key20180107214112_b13-or-29-04-1333) 2003; 1603 Djavaheri-Mergny (key20180107214112_b55-or-29-04-1333) 2010; 29 Zetler (key20180107214112_b66-or-29-04-1333) 1974; 285 Adida (key20180107214112_b46-or-29-04-1333) 2000; 96 Khan (key20180107214112_b21-or-29-04-1333) 2004; 52 Klionsky (key20180107214112_b7-or-29-04-1333) 2000; 290 Slotkin (key20180107214112_b75-or-29-04-1333) 1970; 173 Poirier (key20180107214112_b64-or-29-04-1333) 1966; 89 Herrero-Martín (key20180107214112_b54-or-29-04-1333) 2009; 28 Lamchouri (key20180107214112_b25-or-29-04-1333) 1999; 54 Debnath (key20180107214112_b11-or-29-04-1333) 2005; 1 Beck (key20180107214112_b23-or-29-04-1333) 1986; 65 Akca (key20180107214112_b59-or-29-04-1333) 2006; 54 Mizushima (key20180107214112_b12-or-29-04-1333) 2008; 451 Hanahan (key20180107214112_b39-or-29-04-1333) 2000; 100 Takeuchi (key20180107214112_b61-or-29-04-1333) 2005; 65 Ho (key20180107214112_b63-or-29-04-1333) 1977; 4 Guertin (key20180107214112_b50-or-29-04-1333) 2007; 12 Lin (key20180107214112_b57-or-29-04-1333) 2007; 211 Seglen (key20180107214112_b32-or-29-04-1333) 1982; 79 Abe (key20180107214112_b28-or-29-04-1333) 2011; 34 Zhou (key20180107214112_b56-or-29-04-1333) 2011; 278 List (key20180107214112_b17-or-29-04-1333) 1970 Kirkegaad (key20180107214112_b16-or-29-04-1333) 2004; 2 Deveraux (key20180107214112_b43-or-29-04-1333) 1999; 13 Kim (key20180107214112_b71-or-29-04-1333) 1997; 337 Pattingre (key20180107214112_b52-or-29-04-1333) 2003; 278 Kuo (key20180107214112_b26-or-29-04-1333) 2003; 66 Shao (key20180107214112_b42-or-29-04-1333) 2001; 20 Meley (key20180107214112_b53-or-29-04-1333) 2006; 281 Biederbick (key20180107214112_b30-or-29-04-1333) 1995; 66 Clarke (key20180107214112_b5-or-29-04-1333) 1990; 181 Gozuacik (key20180107214112_b10-or-29-04-1333) 2004; 23 Kawai (key20180107214112_b33-or-29-04-1333) 2007; 3 Loew (key20180107214112_b70-or-29-04-1333) 1985; 28 Viola (key20180107214112_b36-or-29-04-1333) 2012; 8 Rommelspacher (key20180107214112_b62-or-29-04-1333) 1980; 314 Shintani (key20180107214112_b9-or-29-04-1333) 2004; 306 Petiot (key20180107214112_b51-or-29-04-1333) 2002; 27 Li (key20180107214112_b44-or-29-04-1333) 1998; 396 Kishimoto (key20180107214112_b60-or-29-04-1333) 2007; 109 Takeuchi (key20180107214112_b38-or-29-04-1333) 2004; 90 Airaksinen (key20180107214112_b22-or-29-04-1333) 1981; 59 Sobhani (key20180107214112_b24-or-29-04-1333) 2002; 5 Hung (key20180107214112_b37-or-29-04-1333) 2009; 57 Kanzawa (key20180107214112_b3-or-29-04-1333) 2003; 63 Phillips (key20180107214112_b2-or-29-04-1333) 2006; 9 Levine (key20180107214112_b8-or-29-04-1333) 2004; 6 Otsuka (key20180107214112_b15-or-29-04-1333) 1978; 112 Zetler (key20180107214112_b73-or-29-04-1333) 1972; 7 Fadeel (key20180107214112_b4-or-29-04-1333) 1999; 266 Zha (key20180107214112_b41-or-29-04-1333) 2000; 290 DeAngelis (key20180107214112_b1-or-29-04-1333) 2001; 344 Kato (key20180107214112_b47-or-29-04-1333) 2001; 95 Gunn (key20180107214112_b72-or-29-04-1333) 1935; 50 Russo (key20180107214112_b58-or-29-04-1333) 2006; 13 Bruinvels (key20180107214112_b65-or-29-04-1333) 1969; 4 Kabeya (key20180107214112_b31-or-29-04-1333) 2000; 19 Rubinsztein (key20180107214112_b34-or-29-04-1333) 2007; 6 Oliver (key20180107214112_b29-or-29-04-1333) 1998; 273 Gross (key20180107214112_b40-or-29-04-1333) 1999; 274 Yu (key20180107214112_b74-or-29-04-1333) 2003; 305 Corcelle (key20180107214112_b14-or-29-04-1333) 2006; 66 Fu (key20180107214112_b35-or-29-04-1333) 2009; 69 Udenfriend (key20180107214112_b68-or-29-04-1333) 1958; 1 Grella (key20180107214112_b67-or-29-04-1333) 1998; 50 Nadikarni (key20180107214112_b19-or-29-04-1333) 1976 Dymock (key20180107214112_b20-or-29-04-1333) 1976 Abe (key20180107214112_b27-or-29-04-1333) 2009; 20 Levine (key20180107214112_b49-or-29-04-1333) 2005; 115 Naranjo (key20180107214112_b18-or-29-04-1333) 1967 McIsaac (key20180107214112_b69-or-29-04-1333) 1966; 15 Brown (key20180107214112_b6-or-29-04-1333) 2005; 5 |
References_xml | – volume: 65 start-page: 3336 year: 2005 ident: key20180107214112_b61-or-29-04-1333 article-title: Synergistic augmentation of rapamycin-induced autophagy in malignant glioma cells by phosphatidylinositol 3-kinase/protein kinase B inhibitors publication-title: Cancer Res doi: 10.1158/0008-5472.CAN-04-3640 – volume: 95 start-page: 92 year: 2001 ident: key20180107214112_b47-or-29-04-1333 article-title: Expression of surviving in esophageal cancer: correlation with the prognosis and response to chemotherapy publication-title: Int J Cancer doi: 10.1002/1097-0215(20010320)95:2<92::AID-IJC1016>3.0.CO;2-9 – volume: 66 start-page: 3 year: 1995 ident: key20180107214112_b30-or-29-04-1333 article-title: Monodansylcadaverine (MDC) is a specific in vivo marker for autophagic vacuoles publication-title: Eur J Cell Biol – volume: 306 start-page: 990 year: 2004 ident: key20180107214112_b9-or-29-04-1333 article-title: Autophagy in health and disease: a double-edged sword publication-title: Science doi: 10.1126/science.1099993 – volume: 5 start-page: 19 year: 2002 ident: key20180107214112_b24-or-29-04-1333 article-title: An in vitro evaluation of human DNA topoisomerase I inhibition by Peganum harmala L. seed extract and its beta-carboline alkaloids publication-title: Pharm Pharm Sci – volume: 20 start-page: 373 year: 2009 ident: key20180107214112_b27-or-29-04-1333 article-title: Harmol induces apoptosis by caspase-8 activation independently of Fas/Fas ligand interaction in human lung carcinoma H596 cells publication-title: Anticancer Drugs doi: 10.1097/CAD.0b013e32832a2dd9 – volume: 100 start-page: 57 year: 2000 ident: key20180107214112_b39-or-29-04-1333 article-title: The hallmarks of cancer publication-title: Cell doi: 10.1016/S0092-8674(00)81683-9 – volume: 17 start-page: 2100 year: 1999 ident: key20180107214112_b45-or-29-04-1333 article-title: A novel anti-apoptosis gene: re-expression of surviving messenger RNA as a prognosis marker in non-small-cell lung cancers publication-title: J Clin Oncol doi: 10.1200/JCO.1999.17.7.2100 – volume: 290 start-page: 1717 year: 2000 ident: key20180107214112_b7-or-29-04-1333 article-title: Autophagy as a regulated pathway of cellular degradation publication-title: Science doi: 10.1126/science.290.5497.1717 – volume: 109 start-page: 3316 year: 2007 ident: key20180107214112_b60-or-29-04-1333 article-title: The Pten/PI3K pathway governs the homeostasis of Valpha14iNKT cells publication-title: Blood doi: 10.1182/blood-2006-07-038059 – volume: 266 start-page: 699 year: 1999 ident: key20180107214112_b4-or-29-04-1333 article-title: Apoptosis in human disease: a new skin for the old ceremony? publication-title: Biochem Biophys Res Commun doi: 10.1006/bbrc.1999.1888 – volume: 173 start-page: 26 year: 1970 ident: key20180107214112_b75-or-29-04-1333 article-title: Blood levels and urinary excretion of harmine and its metabolites in man and rats publication-title: J Pharmacol Exp Ther – volume: 9 start-page: 157 year: 2006 ident: key20180107214112_b2-or-29-04-1333 article-title: Molecular subclasses of high-grade glioma predict prognosis, delineate a pattern of disease progression, and resemble stages in neurogenesis publication-title: Cancer Cell doi: 10.1016/j.ccr.2006.02.019 – volume: 90 start-page: 1069 year: 2004 ident: key20180107214112_b38-or-29-04-1333 article-title: Inhibition of platelet-derived growth factor signaling induces autophagy in malignant glioma cells publication-title: Br J Cancer doi: 10.1038/sj.bjc.6601605 – volume: 29 start-page: 1717 year: 2010 ident: key20180107214112_b55-or-29-04-1333 article-title: Cross talk between apoptosis and autophagy by caspase-mediated cleavage of Beclin 1 publication-title: Oncogene doi: 10.1038/onc.2009.519 – volume: 6 start-page: 304 year: 2007 ident: key20180107214112_b34-or-29-04-1333 article-title: Potential therapeutic applications of autophagy publication-title: Nat Rev Drug Discov doi: 10.1038/nrd2272 – volume: 13 start-page: 3493 year: 2006 ident: key20180107214112_b58-or-29-04-1333 article-title: Development of novel therapeutic strategies for lung cancer: targeting the cholinergic system publication-title: Curr Med Chem doi: 10.2174/092986706779026192 – volume: 13 start-page: 239 year: 1999 ident: key20180107214112_b43-or-29-04-1333 article-title: IAP family proteins: suppressors of apoptosis publication-title: Genes Dev doi: 10.1101/gad.13.3.239 – volume: 7 start-page: 237 year: 1972 ident: key20180107214112_b73-or-29-04-1333 article-title: Cerebral pharmacokinetics of tremor-producing harmala and iboga alkaloids publication-title: Pharmacology doi: 10.1159/000136294 – volume: 12 start-page: 9 year: 2007 ident: key20180107214112_b50-or-29-04-1333 article-title: Defining the role of mTOR in cancer publication-title: Cancer Cell doi: 10.1016/j.ccr.2007.05.008 – volume: 66 start-page: 6861 year: 2006 ident: key20180107214112_b14-or-29-04-1333 article-title: Disruption of autophagy at the maturation step by the carcinogen lindane is associated with the sustained mitogen-activated protein kinase/extracellular signal-regulated kinase activity publication-title: Cancer Res doi: 10.1158/0008-5472.CAN-05-3557 – volume: 50 start-page: 99 year: 1998 ident: key20180107214112_b67-or-29-04-1333 article-title: Investigation of hallucinogenic and related beta-carbolines publication-title: Drug Alcohol Depend doi: 10.1016/S0376-8716(97)00163-4 – volume: 79 start-page: 1889 year: 1982 ident: key20180107214112_b32-or-29-04-1333 article-title: 3-Methyladenine: specific inhibitor of autophagic/lysosomal protein degradation in isolated rat hepatocytes publication-title: Proc Natl Acad Sci USA doi: 10.1073/pnas.79.6.1889 – volume: 396 start-page: 580 year: 1998 ident: key20180107214112_b44-or-29-04-1333 article-title: Control of apoptosis and mitotic spindle checkpoint by survivin publication-title: Nature doi: 10.1038/25141 – start-page: 385 volume-title: Ethnopharmacological Search for Psychoactive Drugs year: 1967 ident: key20180107214112_b18-or-29-04-1333 article-title: Psychotropic properties of the harmala alkaloids – volume: 66 start-page: 1324 year: 2003 ident: key20180107214112_b26-or-29-04-1333 article-title: Cytotoxic and antimalarial beta-carboline alkaloids from the roots of Eurycoma longifolia publication-title: J Nat Prod doi: 10.1021/np030277n – volume: 273 start-page: 33533 year: 1998 ident: key20180107214112_b29-or-29-04-1333 article-title: Importance of poly(ADP-ribose) polymerase and its cleavage in apoptosis. Lesson from an uncleavable mutant publication-title: J Biol Chem doi: 10.1074/jbc.273.50.33533 – volume: 1603 start-page: 113 year: 2003 ident: key20180107214112_b13-or-29-04-1333 article-title: Autophagy: a barrier or an adaptive response to cancer publication-title: Biochim Biophys Acta – volume: 50 start-page: 379 year: 1935 ident: key20180107214112_b72-or-29-04-1333 article-title: Relations between chemical constitution, pharmacological actions, and therapeutic uses in the harmine group of alkaloids publication-title: Arch Int Pharmacodyn – volume: 4 start-page: 31 year: 1969 ident: key20180107214112_b65-or-29-04-1333 article-title: Influence of drugs on the temperature-lowering effect of harmaline publication-title: Eur J Pharmacol doi: 10.1016/0014-2999(68)90006-X – volume: 285 start-page: 273 year: 1974 ident: key20180107214112_b66-or-29-04-1333 article-title: Pharmacokinetics in the rat of the hallucinogenic alkaloids harmine and harmaline publication-title: Naunyn Shemiedebergs Arch Pharmacol doi: 10.1007/BF00498996 – volume: 278 start-page: 403 year: 2011 ident: key20180107214112_b56-or-29-04-1333 article-title: Bcl-2 and Bcl-xL play important roles in the crosstalk between autophagy and apoptosis publication-title: FEBS J doi: 10.1111/j.1742-4658.2010.07965.x – volume: 19 start-page: 5720 year: 2000 ident: key20180107214112_b31-or-29-04-1333 article-title: LC3, a mammalian homologue of yeast Apg8p, is localized in autophagosome membranes after processing publication-title: EMBO J doi: 10.1093/emboj/19.21.5720 – volume: 20 start-page: 1852 year: 2001 ident: key20180107214112_b42-or-29-04-1333 article-title: Activation of the Fas pathway independently of Fas ligand during apoptosis induced by camptothecin in p53 mutant human colon carcinoma cells publication-title: Oncogene doi: 10.1038/sj.onc.1204264 – volume: 69 start-page: 8967 year: 2009 ident: key20180107214112_b35-or-29-04-1333 article-title: Perifosine inhibits mammalian target of rapamycin signaling through facilitating degradation of major components in the mTOR axis and induces autophagy publication-title: Cancer Res doi: 10.1158/0008-5472.CAN-09-2190 – volume: 8 start-page: 61 year: 2008 ident: key20180107214112_b48-or-29-04-1333 article-title: Survivin, cancer networks and pathway-directed drug discovery publication-title: Nat Rev Cancer doi: 10.1038/nrc2293 – volume: 181 start-page: 195 year: 1990 ident: key20180107214112_b5-or-29-04-1333 article-title: Developmental cell death: morphological diversity and multiple mechanisms publication-title: Anat Embryol doi: 10.1007/BF00174615 – volume: 28 start-page: 677 year: 2009 ident: key20180107214112_b54-or-29-04-1333 article-title: TAK1 activates AMPK-dependent cytoprotective autophagy in TRAIL-treated epithelial cells publication-title: EMBO J doi: 10.1038/emboj.2009.8 – volume: 278 start-page: 16667 year: 2003 ident: key20180107214112_b52-or-29-04-1333 article-title: Amino acids interfere with the ERK1/2-dependent control of macroautophagy by controlling the activation of Raf-1 in human colon cancer HT-29 cells publication-title: J Biol Chem doi: 10.1074/jbc.M210998200 – start-page: 927 volume-title: Indian Material Medica year: 1976 ident: key20180107214112_b19-or-29-04-1333 – volume: 15 start-page: 1625 year: 1966 ident: key20180107214112_b69-or-29-04-1333 article-title: Structure-action relationship of beta-carbolines as monoamine oxidase inhibitors publication-title: Biochem Pharmacol doi: 10.1016/0006-2952(66)90211-5 – volume: 89 start-page: 37 year: 1966 ident: key20180107214112_b64-or-29-04-1333 article-title: Striatal amines, experimental tremor and the effect of harmaline in the monkey publication-title: Brain doi: 10.1093/brain/89.1.37 – volume: 344 start-page: 114 year: 2001 ident: key20180107214112_b1-or-29-04-1333 article-title: Brain tumors publication-title: N Engl J Med doi: 10.1056/NEJM200101113440207 – volume: 27 start-page: 431 year: 2002 ident: key20180107214112_b51-or-29-04-1333 article-title: Diversity of signaling controls of macroautophagy in mammalian cells publication-title: Cell Struct Funct doi: 10.1247/csf.27.431 – volume: 59 start-page: 21 year: 1981 ident: key20180107214112_b22-or-29-04-1333 article-title: β-carbolines, psychoactive compounds in the mammalian body. Part I: occurrence, origin and metabolism publication-title: Med Biol – volume: 52 start-page: 394 year: 2004 ident: key20180107214112_b21-or-29-04-1333 article-title: Transport of human alkaloids across Caco-2 cell monolayers publication-title: Chem Pharm Bull doi: 10.1248/cpb.52.394 – volume: 8 start-page: 16 year: 2012 ident: key20180107214112_b36-or-29-04-1333 article-title: MG-2477, a new tubulin inhibitor, induces autophagy through inhibition of the Akt/mTOR pathway and delayed apoptosis in A549 cells publication-title: Biochem Pharmacol doi: 10.1016/j.bcp.2011.09.017 – volume: 5 start-page: 231 year: 2005 ident: key20180107214112_b6-or-29-04-1333 article-title: The role of apoptosis in cancer development and treatment response publication-title: Nat Rev Cancer doi: 10.1038/nrc1560 – volume: 451 start-page: 1069 year: 2008 ident: key20180107214112_b12-or-29-04-1333 article-title: Autophagy fights disease through cellular self-digestion publication-title: Nature doi: 10.1038/nature06639 – volume: 274 start-page: 1156 year: 1999 ident: key20180107214112_b40-or-29-04-1333 article-title: Caspase cleaved BID targets mitochondria and is required for cytochrome c release, while BCL-XL prevents this release but not tumor necrosis factor-R1/Fas death publication-title: J Biol Chem doi: 10.1074/jbc.274.2.1156 – volume-title: Hager’s Hand book for Pharmaceutical Practice year: 1970 ident: key20180107214112_b17-or-29-04-1333 – volume: 4 start-page: 151 year: 1977 ident: key20180107214112_b63-or-29-04-1333 article-title: Pharmacological and biochemical studies with beta-carboline analogs publication-title: Curr Dev Psychopharmacol – volume: 54 start-page: 753 year: 1999 ident: key20180107214112_b25-or-29-04-1333 article-title: Antitumor principles from Peganum harmala seeds publication-title: Therapie – volume: 281 start-page: 34870 year: 2006 ident: key20180107214112_b53-or-29-04-1333 article-title: AMP-activated protein kinase and the regulation of autophagic proteolysis publication-title: J Biol Chem doi: 10.1074/jbc.M605488200 – volume: 337 start-page: 137 year: 1997 ident: key20180107214112_b71-or-29-04-1333 article-title: Inhibition of monoamine oxidase A by β-carboline derivatives publication-title: Arch Biochem Biophys doi: 10.1006/abbi.1996.9771 – volume: 6 start-page: 463 year: 2004 ident: key20180107214112_b8-or-29-04-1333 article-title: Development by self-digestion: molecular mechanisms and biological functions of autophagy publication-title: Dev Cell doi: 10.1016/S1534-5807(04)00099-1 – volume: 305 start-page: 315 year: 2003 ident: key20180107214112_b74-or-29-04-1333 article-title: Contribution of individual cytochrome P450 isozymes to the O-demethylation of the psychotropic beta-carboline alkaloids harmaline and harmine publication-title: J Pharmacol Exp Ther doi: 10.1124/jpet.102.047050 – volume: 54 start-page: 25 year: 2006 ident: key20180107214112_b59-or-29-04-1333 article-title: Activation of the AKT and STAT3 pathways and prolonged survival by a mutant EGFR in human lung cancer cells publication-title: Lung Cancer doi: 10.1016/j.lungcan.2006.06.007 – volume: 63 start-page: 2103 year: 2003 ident: key20180107214112_b3-or-29-04-1333 article-title: Induction of autophagic cell death in malignant glioma cells by arsenic trioxide publication-title: Cancer Res – volume: 96 start-page: 1921 year: 2000 ident: key20180107214112_b46-or-29-04-1333 article-title: Prognostic significance of surviving expression in diffuse large B-cell lymphomas publication-title: Blood – volume: 112 start-page: 127 year: 1978 ident: key20180107214112_b15-or-29-04-1333 article-title: Differences in the rates of protein degradation in untransformed and transformed cell lines publication-title: Exp Cell Res doi: 10.1016/0014-4827(78)90533-5 – volume: 1 start-page: 160 year: 1958 ident: key20180107214112_b68-or-29-04-1333 article-title: Studies with reversible inhibitors of monoamine oxidase: harmaline and related compounds publication-title: Biochem Pharmacol doi: 10.1016/0006-2952(58)90025-X – volume: 1 start-page: 66 year: 2005 ident: key20180107214112_b11-or-29-04-1333 article-title: Does autophagy contribute to cell death? publication-title: Autophagy doi: 10.4161/auto.1.2.1738 – volume: 211 start-page: 771 year: 2007 ident: key20180107214112_b57-or-29-04-1333 article-title: Transactivation of Src, PDGF receptor, and Akt is involved in IL-1beta-induced ICAM-1 expression in A549 cells publication-title: J Cell Physiol doi: 10.1002/jcp.20987 – volume: 28 start-page: 17 year: 1985 ident: key20180107214112_b70-or-29-04-1333 article-title: Theoretical structure-activity studies of beta-carboline analogs. Requirements for benzodiazepine receptor affinity and antagonist activity publication-title: Mol Pharmacol – volume: 314 start-page: 97 year: 1980 ident: key20180107214112_b62-or-29-04-1333 article-title: 1-Methyl-beta-carboline (harmane), a potent endogenous inhibitor of benzodiazepine receptor binding publication-title: Naunyn Schmiedebergs Arch Pharmacol doi: 10.1007/BF00498436 – volume: 115 start-page: 2679 year: 2005 ident: key20180107214112_b49-or-29-04-1333 article-title: Autophagy in cell death: an innocent convict? publication-title: J Clin Invest doi: 10.1172/JCI26390 – volume: 34 start-page: 1264 year: 2011 ident: key20180107214112_b28-or-29-04-1333 article-title: The β-carboline alkaloid harmol induces cell death via autophagy but not apoptosis in human non-small cell lung cancer A549 cells publication-title: Biol Pharm Bull doi: 10.1248/bpb.34.1264 – volume: 3 start-page: 154 year: 2007 ident: key20180107214112_b33-or-29-04-1333 article-title: Autophagosome-lysosome fusion depends on the pH in acidic compartments in CHO cells publication-title: Autophagy doi: 10.4161/auto.3634 – volume: 57 start-page: 9809 year: 2009 ident: key20180107214112_b37-or-29-04-1333 article-title: 6-Shogaol, an active constituent of dietary ginger, induces autophagy by inhibiting the AKT/mTOR pathway in human non-small cell lung cancer A549 cells publication-title: J Agric Food Chem doi: 10.1021/jf902315e – volume: 23 start-page: 2891 year: 2004 ident: key20180107214112_b10-or-29-04-1333 article-title: Autophagy as a cell death and tumor suppressor mechanism publication-title: Oncogene doi: 10.1038/sj.onc.1207521 – volume: 65 start-page: 97 year: 1986 ident: key20180107214112_b23-or-29-04-1333 article-title: Concentrations of the enantiomers of 5-hydroxymethylptoline in mammalian urine: Implications for in vivo biosynthesis publication-title: Biochem Pharmacol – volume: 290 start-page: 1761 year: 2000 ident: key20180107214112_b41-or-29-04-1333 article-title: Posttranslational N-myristoylation of BID as a molecular switch for targeting mitochondria and apoptosis publication-title: Science doi: 10.1126/science.290.5497.1761 – start-page: 252 volume-title: Pharmacopia Indica year: 1976 ident: key20180107214112_b20-or-29-04-1333 – volume: 2 start-page: 301 year: 2004 ident: key20180107214112_b16-or-29-04-1333 article-title: Cellular autophagy: surrender, avoidance and subversion by microorganisms publication-title: Nat Rev Microbiol doi: 10.1038/nrmicro865 |
SSID | ssib004298979 ssib028798691 ssj0027069 |
Score | 2.0290477 |
SourceID | crossref nii |
SourceType | Enrichment Source Index Database Publisher |
StartPage | 1333 |
SubjectTerms | Apoptosis Autophagy Brain Neoplasms Cell Line, Tumor Down-Regulation Gene Expression Regulation, Neoplastic Glioma Harmine Humans Inhibitor of Apoptosis Proteins Proto-Oncogene Proteins c-akt RNA, Small Interfering Signal Transduction Survivin TOR Serine-Threonine Kinases |
Title | Harmol induces autophagy and subsequent apoptosis in U251MG human glioma cells through the downregulation of survivin |
URI | https://cir.nii.ac.jp/crid/1872272492913725568 |
Volume | 29 |
hasFullText | 1 |
inHoldings | 1 |
isFullTextHit | |
isPrint | |
link | http://utb.summon.serialssolutions.com/2.0.0/link/0/eLvHCXMwnV1bb9MwFLZgkxAviKsYY8gP8BRl1LFzeyxoUIE6EKxS3yonjkfoFldJswd-PefEbpIhJi5S5Vau5VY-n46_c2J_h5CXQkeRjnXsh0WkfCEm2k9ElvtxlquJ0IFQXU53fhrNFuLDMlwOlQq72yXb7Dj_8dt7Jf9jVegDu-It2X-wbD8pdMBnsC-0YGFo_8rGM1lfGhTNUC0erJItqgRIJ6nUgEvozkmjcLjZbA1Kj5SVtwCuMX_vivOdX5TmUnqYvm_6mj3IRRVE57WtU-8oZdOCV7lyQt2Ozn6qcqvhZHl8z8-n6_Jb2Uhvmg24KWuzNt5Hs24zOc41YN0HMc41fN3gVRtlmhtyilgm3Oc8XNrNxfbFKfMD4Vy9c7kuyWF9JkTJfLT_Mm7ltn717cCsUCvWoIgr48dAPWDn3Q8gOgD3tv_m5PTzl_Emm6TD40eICtOkEwXaReKTrtZh_3_tjQj8hdfj-a9xldtVWY6ox9l9cs_FDHRqAfCA3PouH5I7c3cq4hFpLQ6owwHtcUBhIemAA9rjAIZSiwPa4YBaHNAOB9ThAN4Leh0H1Gi6w8Fjsnh3cvZ25rtyGn6OVcj8TEAwHGY8VVxqJvIg1nmchYGOZITMOdUJK4CwcIgitdBhmKdRNyzWqoAXf0L2KlMVTwmdSMWBqgYywNrlgmVcMcFEmOYqUinTB8TbLdwqd1rzWPLkYgUxJy7zytQrXOYVLvMBedWP3liNlRvGHYENYEJsWRIHQYx6lynjcSek9-wP3x-SuwOon5O9bd0WR0Apt9kLB6Cf2P10Ig |
linkProvider | ProQuest |
openUrl | ctx_ver=Z39.88-2004&ctx_enc=info%3Aofi%2Fenc%3AUTF-8&rfr_id=info%3Asid%2Fsummon.serialssolutions.com&rft_val_fmt=info%3Aofi%2Ffmt%3Akev%3Amtx%3Ajournal&rft.genre=article&rft.atitle=Harmol+induces+autophagy+and+subsequent+apoptosis+in+U251MG+human+glioma+cells+through+the+downregulation+of+survivin&rft.jtitle=Oncology+Reports&rft.au=Akihisa+Abe&rft.au=Hiroko+Kokuba&rft.date=2013-04-01&rft.pub=Spandidos+Publications&rft.issn=1021-335X&rft.eissn=1791-2431&rft.volume=29&rft.spage=1333&rft.epage=1342&rft_id=info:doi/10.3892%2For.2013.2242 |
thumbnail_l | http://covers-cdn.summon.serialssolutions.com/index.aspx?isbn=/lc.gif&issn=1021-335X&client=summon |
thumbnail_m | http://covers-cdn.summon.serialssolutions.com/index.aspx?isbn=/mc.gif&issn=1021-335X&client=summon |
thumbnail_s | http://covers-cdn.summon.serialssolutions.com/index.aspx?isbn=/sc.gif&issn=1021-335X&client=summon |