Field Effectiveness of a Typhoid Conjugate Vaccine: The 2018 Navi Mumbai Pediatric TCV Campaign

• Published in: The American journal of tropical medicine and hygiene Vol. 111; no. 4; pp. 848 - 852
• Main Authors: Date, Kashmira, LeBoa, Christopher, Hoffman, Seth A, Haldar, Pradeep, Harvey, Pauline, An, Qian, Zhang, Chenhua, Yewale, Vijay N, Daruwalla, Savita, Dharmapalan, Dhanya, Gavhane, Jeetendra, Joshi, Shrikrishna, Rai, Rajesh, Rathod, Varsha, Shetty, Keertana, Warrier, Divyalatha S, Yadav, Shalini, Shimpi, Rahul, Jayaprasad, Niniya, Horng, Lily, Fagerli, Kirsten, Borhade, Priyanka, Chakraborty, Debjit, Katkar, Arun, Kunwar, Abhishek, Andrews, Jason R, Bahl, Sunil, Bhatnagar, Pankaj, Dutta, Shanta, Luby, Stephen P
• Format: Journal Article
• Language: English
• Published: United States Institute of Tropical Medicine 02.10.2024; The American Society of Tropical Medicine and Hygiene
• Subjects: Adolescent; Child; Child, Preschool; Female; Humans; India - epidemiology; Infant; Male; Mass Vaccination; Salmonella typhi - immunology; Short Report; Typhoid Fever - epidemiology; Typhoid Fever - prevention & control; Typhoid-Paratyphoid Vaccines - administration & dosage; Typhoid-Paratyphoid Vaccines - immunology; Vaccine Efficacy; Vaccines, Conjugate - immunology; India

Typbar-TCV®, a typhoid conjugate vaccine (TCV), was prequalified by the World Health Organization in 2017. We evaluated its effectiveness in a mass vaccination program targeting children 9 months to 14 years in Navi Mumbai, India, from September 2018 to July 2020. We compared laboratory-confirmed ty...