Flaxseed and mulberry extract improve trabecular bone quality in estrogen-deficient rats

• Published in: Climacteric : the journal of the International Menopause Society Vol. 28; no. 2; pp. 175 - 183
• Main Authors: Jacques, Larissa Sampaio, Pereira, Jéssica Petrine Castro, Santos, Beatriz Menegate, Barrioni, Breno Rocha, Del Bianco Borges, Bruno
• Format: Journal Article
• Language: English
• Published: England Taylor & Francis Ltd 01.04.2025
• Subjects: Acids; Alkaline Phosphatase - blood; Animals; Bone Density - drug effects; Bones; Cancellous Bone - drug effects; Estrogens; Estrogens - deficiency; Female; Flax - chemistry; Morus - chemistry; Osteoporosis - prevention & control; Ovariectomy; Plant Extracts - pharmacology; Rats; Rats, Wistar; osteopenia; phenolic compounds; menopause; estrogenic action; Antioxidant power

Many hormones, including estrogens, modulate bone metabolism, which plays a crucial role in maintaining bone health. Estrogen depletion, as occurs in menopause, leads to increased bone resorption and decreased formation, resulting in osteopenia/osteoporosis. This study investigates the effects of fl...