Comparison of receptive field expansion produced by GABAB and GABAA receptor antagonists in raccoon primary somatosensory cortex

• Published in: Experimental brain research Vol. 144; no. 1; pp. 114 - 121
• Main Authors: CHOWDHURY, S. A, RASMUSSON, D. D
• Format: Journal Article
• Language: English
• Published: Berlin Springer 01.05.2002; Springer Nature B.V
• Subjects: Biological and medical sciences; Fundamental and applied biological sciences. Psychology; Somesthesis and somesthetic pathways (proprioception, exteroception, nociception); interoception; electrolocation. Sensory receptors; Vertebrates: nervous system and sense organs; Fissipedia; Carnivora; Receptive field; Central nervous system; Discharge pattern; Gabaergic transmission; Electrophysiology; Synaptic inhibition; Somatosensory cortex; Procyon lotor; Vertebrata; Mammalia; Somesthetic pathway; Neurotransmitter; GABA; Gabaergic receptor B; Gabaergic receptor A; Brain (vertebrata)

Recordings were made from 62 neurons in the forepaw representation of primary somatosensory cortex in anesthetized raccoons. Microiontophoretic administration of a specific GABAB receptor antagonist, CGP 55845, produced receptive field expansion in 74% of 46 neurons, in which it was tested first. Th...