Conformal Partial Brain Irradiation Versus Stereotactic Radiation Therapy in the Management of Resected Brain Metastases: A Retrospective Study

• Published in: Curēus (Palo Alto, CA) Vol. 17; no. 1; p. e77762
• Main Authors: Shah, Sophia N, Shah, Sohan S, Shukla, Gaurav, Shah, Sunjay A
• Format: Journal Article
• Language: English
• Published: United States Springer Nature B.V 01.01.2025; Cureus
• Subjects: Brain research; Cancer therapies; Dosimetry; Failure; Life expectancy; Lung cancer; Melanoma; Metastasis; Necrosis; Neurosurgery; Oncology; Ovarian cancer; Patients; Planning; Radiation Oncology; Radiation therapy; Radiosurgery; Statistical analysis; Surgery; Tissues; United States > US; stereotactic radiotherapy (srt); whole-brain radiotherapy; leptomeningeal enhancement; treatment of brain metastases; 3d-conformal radiation therapy
• ISSN: 2168-8184; 2168-8184
• DOI: 10.7759/cureus.77762

The standard of care after resection of a single brain metastasis is to treat the cavity with stereotactic radiation therapy (SRT) to minimize the risk of recurrence. However, a prospective randomized trial of SRT demonstrated higher than expected rates of local recurrence, possibly due to geographi...