The Evaluation of Glypican-3 mRNA and Alpha-fetoprotein mRNA as biomarker for hepatocellular carcinoma in Dogs: A preliminary study

• Published in: Veterinary Integrative Sciences (Online) Vol. 23; no. 3
• Main Authors: Phosri, Aphinan, Pringproa, Kidsadagon, Thitaram, Niyada, Chantawong, Pinkarn, Chuammitri, Phongsakorn, =Thongtharb, Atigan
• Format: Journal Article
• Language: English
• Published: Faculty of Veterinary Medicine, Chiang Mai University 01.09.2025

Glypican-3 (GPC-3) and alpha-fetoprotein (AFP) are considered powerful biomarkers for human hepatocellular carcinoma (HCC). The elevation of GPC-3 and AFP gene expression is commonly found in individual HCC patients. The detection of these biomarkers can be achieved with the examination of blood or...