Proliferative and anti-proliferative effects of thymosin α1 on cells are associated with manipulation of cellular ROS levels

• Published in: Chemico-biological interactions Vol. 180; no. 3; pp. 383 - 388
• Main Authors: Qin, Yong, Chen, Fu-Ding, Zhou, Liang, Gong, Xing-Guo, Han, Qi-Feng
• Format: Journal Article
• Language: English
• Published: Elsevier Ireland Ltd 14.08.2009
• Subjects: Akt pathway; Cell cycle; ROS; Thymosin α1; Thymosin α1; Akt pathway; ROS; Cell cycle

Reactive oxygen species (ROS) are constantly generated and eliminated in the biological system and play important roles in a variety of physiological and pathological processes. Previous studies indicate that modulation of cellular ROS affects cell proliferation. Thymosin alpha 1 (Tα1) is a naturall...