Screening for cancer of the colon and rectum A review on incidence, mortality, cost and benefit

Key words: Colorectal cancer, Screening, Incidence, Mortality, Cost-effectiveness In this article the incidence and mortality for cancer of the colon and rectum in Iceland is discussed. The two most common screening methods, faecal immunochemical test (FIT) and colonoscopy are compared and an estima...

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Published inLaeknabladid Vol. 107; no. 9; pp. 398 - 405
Main Authors Birgisson, Helgi, Ólafsdóttir, Elínborg J., Sverrisdóttir, Anna, Einarsson, Sigurður, Smáradóttir, Agnes, Tryggvadóttir, Laufey
Format Journal Article
LanguageEnglish
Published 03.09.2021
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Abstract Key words: Colorectal cancer, Screening, Incidence, Mortality, Cost-effectiveness In this article the incidence and mortality for cancer of the colon and rectum in Iceland is discussed. The two most common screening methods, faecal immunochemical test (FIT) and colonoscopy are compared and an estimate of cost and benefits for the Icelandic society will be made. The incidence of cancer of the colon and rectum has been increasing in Iceland in last decades but mortality has decreased and survival improved. However, more individuals die from cancer of the colon and rectum than from both breast- and cervical cancer added together. It is likely that screening for cancer of the colon and rectum, could prevent at least 6 of the 28 deaths related to those cancers, occurring yearly in Iceland in screening age, given a screening ages of 50-74 years. The extra cost for the Icelandic community due to the implementation of screening for cancer of the colon and rectum will be acceptable due to the lower cost of simpler treatments, lower cancer incidence and reduced mortality.
AbstractList Key words: Colorectal cancer, Screening, Incidence, Mortality, Cost-effectiveness In this article the incidence and mortality for cancer of the colon and rectum in Iceland is discussed. The two most common screening methods, faecal immunochemical test (FIT) and colonoscopy are compared and an estimate of cost and benefits for the Icelandic society will be made. The incidence of cancer of the colon and rectum has been increasing in Iceland in last decades but mortality has decreased and survival improved. However, more individuals die from cancer of the colon and rectum than from both breast- and cervical cancer added together. It is likely that screening for cancer of the colon and rectum, could prevent at least 6 of the 28 deaths related to those cancers, occurring yearly in Iceland in screening age, given a screening ages of 50-74 years. The extra cost for the Icelandic community due to the implementation of screening for cancer of the colon and rectum will be acceptable due to the lower cost of simpler treatments, lower cancer incidence and reduced mortality.
Author Ólafsdóttir, Elínborg J.
Sverrisdóttir, Anna
Tryggvadóttir, Laufey
Birgisson, Helgi
Einarsson, Sigurður
Smáradóttir, Agnes
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CitedBy_id crossref_primary_10_3389_fmicb_2022_953905
crossref_primary_10_1155_2023_8709458
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crossref_primary_10_1080_14728222_2024_2331015
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CorporateAuthor andspitali, National University Hospital of Iceland, Dept of Gastroenterology. Reykjavík Digestive Center
Icelandic Cancer Registry, Icelandic Cancer Society Research Center. Department of Surgical Sciences, Colorectal Surgery, Uppsala University, Sweden
Icelandic Cancer Registry, Icelandic Cancer Society Research Center. University of Iceland, BioMedical Center
Landspitali, National University Hospital of Iceland, Dept of Oncology
Center of Medical Gastroenterology, the Medical Clinic, Glæsibæ, Iceland
celandic Cancer Registry, Icelandic Cancer Society Research Center
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– name: Icelandic Cancer Registry, Icelandic Cancer Society Research Center. Department of Surgical Sciences, Colorectal Surgery, Uppsala University, Sweden
– name: andspitali, National University Hospital of Iceland, Dept of Gastroenterology. Reykjavík Digestive Center
– name: Landspitali, National University Hospital of Iceland, Dept of Oncology
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