Level of Expression of IL-13Rα2 Impacts Receptor Distribution and IL-13 Signaling
Abstract IL-13, a critical cytokine for allergic inflammation, exerts its effects through a complex receptor system including IL-4Rα, IL-13Rα1, and IL-13Rα2. IL-4Rα and IL-13Rα1 form a heterodimeric signaling receptor for IL-13. In contrast, IL-13Rα2 binds IL-13 with high affinity but does not signa...
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Published in | The Journal of immunology (1950) Vol. 176; no. 12; pp. 7495 - 7501 |
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Main Authors | , , , , , , |
Format | Journal Article |
Language | English |
Published |
15.06.2006
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Online Access | Get full text |
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