An octavalent dendrimer of multiple antigenic peptide with a property of pan-coronavirus IgM induction improved clinical signs of feline infectious peritonitis in cats

• Published in: Veterinary vaccine Vol. 3; no. 1; p. 100055
• Main Authors: Nara, Takuya, Shimoda, Hiroshi, Suzuki, Chitose, Tran, Ngo Thuy Bao, Tsukada, Hina, Okayama, Hiroki, Weiyin, Hu, Obata, Miho, Mitsunaga, Saki, Sakurai, Masashi, Kuroda, Yudai, Maeda, Ken, Kubo, Masato, Saito, Takashi, Masuda, Kenichi
• Format: Journal Article
• Language: English
• Published: Elsevier B.V 01.03.2024; Elsevier
• Subjects: Cats; Coronaviruses; FIP; IgM; Multiple antigenic peptides; Universal vaccine; Cats; Coronaviruses; FIP; Multiple antigenic peptides; Universal vaccine; IgM

Feline infectious peritonitis (FIP) is a lethal disease caused by a pathogenic coronavirus, feline infectious peritonitis virus (FIPV), in cats. Effective vaccines have been unsuccessful due to the frequent mutation of FIPV and antibody-dependent enhancement (ADE) caused by vaccine-induced IgG antib...