Catalyst- and oxidant-free electrooxidative site-selective [3/4 + 2] annulation to fused polycyclic heteroaromatics

• Published in: Green chemistry : an international journal and green chemistry resource : GC Vol. 24; no. 13; pp. 5191 - 5196
• Main Authors: Guan, Wenjing, Ying, Ke, Yuan, Chengcheng, Hang, Jinlin, Liu, Chengkou, Huang, Xiangxing, Fang, Zheng, Guo, Kai
• Format: Journal Article
• Language: English
• Published: Cambridge Royal Society of Chemistry 04.07.2022
• Subjects: Adaptability; Alkynes; Aromatic compounds; Atom economy; Catalysts; Chemical reactions; Electrochemical oxidation; Electrochemistry; Functional groups; Green chemistry; Heterocyclic compounds; Labeling; Organic chemistry; Oxidants; Oxidation; Oxidizing agents; Pyridines; Regioselectivity; Substrates; Transition metals

Annulation π-extension of arenes with alkynes is a straightforward and practical strategy for the rapid construction of polycyclic aromatic compounds. Recently, some intriguing transition-metal-catalyzed polycyclic arene syntheses were described. However, metal catalysts and exogenous oxidants were...