Photocatalyst-, metal- and additive-free, direct C-H arylation of quinoxalin-2(1H)-ones with aryl acyl peroxides induced by visible light

• Published in: ORGANIC CHEMISTRY FRONTIERS Vol. 7; no. 24; pp. 4031 - 4042
• Main Authors: Xu, Jun, Zhang, Hongdou, Zhao, Jianming, Ni, Zhigang, Zhang, Pengfei, Shi, Bing-Feng, Li, Wanmei
• Format: Journal Article
• Language: English
• Published: CAMBRIDGE Royal Soc Chemistry 14.12.2020; Royal Society of Chemistry
• Subjects: Aromatic compounds; Catalysts; Chemistry; Chemistry, Organic; Organic chemistry; Peroxides; Photocatalysts; Physical Sciences; Science & Technology; POTENT; QUINOXALINONES; DECARBOXYLATIVE ORTHO-ARYLATION; AGENTS; INHIBITORS; AROMATIC-SUBSTITUTION; BENZOYL PEROXIDE; BOND; ASYMMETRIC ALPHA-BENZOYLOXYLATION; PHOTOREDOX CATALYSIS

A visible light-mediated direct C-H arylation of quinoxalin-2(1H)-ones with aryl acyl peroxides has been developed. The reaction proceeds smoothly through a radical process in the absence of photocatalyst, additive and metal catalyst, providing the corresponding products in moderate to good yields....