Knockdown of LncRNA-XIST Suppresses Proliferation and TGF-β1-Induced EMT in NSCLC Through the Notch-1 Pathway by Regulation of miR-137

• Published in: Genetic testing and molecular biomarkers
• Main Authors: Wang, Xi, Zhang, Guojun, Cheng, Zhe, Dai, Lingling, Jia, Liuqun, Jing, Xiaogang, Wang, Huan, Zhang, Rui, Liu, Meng, Jiang, Tianci, Yang, Yuanjian, Yang, Meng
• Format: Journal Article
• Language: English
• Published: United States 01.06.2018
• Subjects: miR-137; NSCLC; proliferation; EMT; lncRNA-XIST

Noncoding RNAs (ncRNAs), primarily microRNAs and long ncRNAs, play important roles in lung cancer. However, the role of long ncRNA (lncRNA)-X-inactive specific transcript (XIST) in non-small-cell lung cancer (NSCLC) is unclear. The purpose of this study was to explore the biologic function and poten...