Cardioprotective microRNAs (protectomiRs) in a pig model of acute myocardial infarction and cardioprotection by ischaemic conditioning: MiR-450a

• Published in: British journal of pharmacology
• Main Authors: Nagy, Regina N, Makkos, András, Baranyai, Tamás, Giricz, Zoltán, Szabó, Márta, Kravcsenko-Kiss, Bernadett, Bereczki, Zoltán, Ágg, Bence, Puskás, László G, Faragó, Nóra, Schulz, Rainer, Gyöngyösi, Mariann, Lukovic, Dominika, Varga, Zoltán V, Görbe, Anikó, Ferdinandy, Péter
• Format: Journal Article
• Language: English
• Published: England 18.09.2024
• Subjects: postconditioning; protectomiR; miR‐450a; microRNA; miR‐451; remote conditioning; pig; preconditioning

Cardioprotective miRNAs (protectomiRs) are promising therapeutic tools. Here, we aimed to identify protectomiRs in a translational porcine model of acute myocardial infarction (AMI) and to validate their cardiocytoprotective effect. ProtectomiR candidates were selected after systematic analysis of m...