A TRIAL OF P-ERG FOR THE AID OF THERAPY IN AMBLYOPIA (2)

Pattern-reversal electroretinogram (P-ERG) was taken in 56 eyes of 28 subjects, 13 males and 15 females aged 4 to 9 years old with anisometropic, ametropic and strabismic amblyopia who had good central fixation and were otherwise healthy children. As reported by Arden, the ratio of response amplitud...

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Published inJAPANESE ORTHOPTIC JOURNAL Vol. 18; pp. 126 - 131
Main Authors IDE, Kayoko, YAMAMOTO, Misao, SHINKAI, Tsuneichi, NOMURA, Khoji, TAKAYAMA, Shozo
Format Journal Article
LanguageEnglish
Published JAPANESE ASSOCIATION OF CERTIFIED ORTHOPTISTS 1990
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ISSN0387-5172
1883-9215
DOI10.4263/jorthoptic.18.126

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Abstract Pattern-reversal electroretinogram (P-ERG) was taken in 56 eyes of 28 subjects, 13 males and 15 females aged 4 to 9 years old with anisometropic, ametropic and strabismic amblyopia who had good central fixation and were otherwise healthy children. As reported by Arden, the ratio of response amplitude of amblyopic eyes to that of fellow eyes was higher than 0.8 in 80% of those children with anisometropic and ametropic amblyopia and in 89% with strabismic amblyopia. The visual acuity of those patients was improved by the subsequent orthoptic treatment. In all of those children tested this time, the similar results were obtained; the ratio was higher than 0.9.
AbstractList Pattern-reversal electroretinogram (P-ERG) was taken in 56 eyes of 28 subjects, 13 males and 15 females aged 4 to 9 years old with anisometropic, ametropic and strabismic amblyopia who had good central fixation and were otherwise healthy children. As reported by Arden, the ratio of response amplitude of amblyopic eyes to that of fellow eyes was higher than 0.8 in 80% of those children with anisometropic and ametropic amblyopia and in 89% with strabismic amblyopia. The visual acuity of those patients was improved by the subsequent orthoptic treatment. In all of those children tested this time, the similar results were obtained; the ratio was higher than 0.9.
Author SHINKAI, Tsuneichi
TAKAYAMA, Shozo
NOMURA, Khoji
YAMAMOTO, Misao
IDE, Kayoko
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  fullname: SHINKAI, Tsuneichi
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  fullname: NOMURA, Khoji
  organization: Dept, Ophthalmol Kobe Children's Hospital
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  fullname: TAKAYAMA, Shozo
  organization: Dept, Ophthalmol Kobe Children's Hospital
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References 17) 宮澤裕之, 関谷善文他:パターンERGの早期緑内障検出能力の検討. 日眼92, 156-160, 1988.
8) 高山昇三, 野村耕治 他:パターンERGの弱視治療への応用. 眼臨投稿中.
12) G. E. Holder: Significance of abnormal pattern electroretinography in anterior visual pathway dysfunction. Bri. J. Ophthal. 71, 166-171, 1987.
3) G. B. Arden & S. L. Wooding: Pattern ERG in Amblyopia. Invest. Ophthal. Vis. Sci. Vol 26, 88-96, 1985.
6) I. Gottlob & L. Welge-Lussent: Nomal pattern electroretinogram in amblyopia. Invest. Ophthal. Vis. Sci. Vol 28, 187-191, 1987.
9) L. Maffei & A. Fiorentini: Electroretinographic responses to alternating gratings before and after section of the optic nerve. Science 211, 953-955, 1981.
10) L. Maffei, A. Fiorentini et al: Pattern ERG in the monkey after section of the optic nerve. Exp. Brain Res. 59, 423-425, 1985.
18) H. Ikeda: Visual acuity, its development and amblyopia. J. Royal Sosiety of Med. Vol 73, 546-555, 1980.
1) G. B. Arden, Vaegan et al: Pattern ERGs are abnormal in many amblyopes. Trans. Ophthal. Soc. U. K. 100, 453-460, 1980.
14) G. L. Trick: PRRP abnormalities in glaucoma and ocular hypertention. Invest. Ophthal Vis. Sci. 27, 1730-1736, 1986.
4) P. Wanger & H. E. Persson: Oscillatory potentials, flash and pattern-reversal electroretinogram in amblyopia. Acta Ophthalmologica, 62, 143-650, 1984.
19) H. Ikeda & K. E. Tremain: Amblyopia resulting from penalisation; neurophysiological studies of kittens reared with atropinisation of one or both eyes. Bri. J. Ophthal. 62, 21-28, 1978.
5) H. E. Persson & P. Wanger: Pattern-reversal electroretinogram in squint amblyopia, artificial anisometropia and simulated eccentric fixation. Acta Ophthalmologica, 60, 123-132, 1982.
13) G. G. Celesia, D. Kaufman et al: Simaltaneuos recording of pattern electroretinography and visual evoked potentials in multiple sclerosis. A method to separate demyelination from axonal damage to the optic nerve. Arch. Neurology, 43, 1247-1252, 1986.
11) C. Teping & A. Goeneberg: Physiological Basis and Clinical Application of Pattern Electroretinogram. Dev. Ophthal. Vol 9. 74-80, 1984.
7) R. F. Hess, C. L. Baker et al: The pattern evoked electroretinogram; Its variability in normals and its relationshop to amblyopia. Invest. Ophthal. Vis. Sci. Vol 26, 1610-1623, 1985.
16) 新井三樹, 直井信久他:Pattern ERG, VEPにおける測定誤差について. 臨眼80, 1751-1756, 1986.
15) 千原悦夫, 森秀夫他:パターンERGによる緑内障視神経障害の検出. 臨眼41, 521-524, 1987.
2) G. B. Arden, Vaegan et al: Clinical and experimental evidence that the pattern electroretinogram (PERG) is generated in more proximal retinal layers than the focal electroretinogram (FERG). Annals NYAS. 580-601, 1982.
References_xml – reference: 11) C. Teping & A. Goeneberg: Physiological Basis and Clinical Application of Pattern Electroretinogram. Dev. Ophthal. Vol 9. 74-80, 1984.
– reference: 8) 高山昇三, 野村耕治 他:パターンERGの弱視治療への応用. 眼臨投稿中.
– reference: 10) L. Maffei, A. Fiorentini et al: Pattern ERG in the monkey after section of the optic nerve. Exp. Brain Res. 59, 423-425, 1985.
– reference: 14) G. L. Trick: PRRP abnormalities in glaucoma and ocular hypertention. Invest. Ophthal Vis. Sci. 27, 1730-1736, 1986.
– reference: 2) G. B. Arden, Vaegan et al: Clinical and experimental evidence that the pattern electroretinogram (PERG) is generated in more proximal retinal layers than the focal electroretinogram (FERG). Annals NYAS. 580-601, 1982.
– reference: 15) 千原悦夫, 森秀夫他:パターンERGによる緑内障視神経障害の検出. 臨眼41, 521-524, 1987.
– reference: 7) R. F. Hess, C. L. Baker et al: The pattern evoked electroretinogram; Its variability in normals and its relationshop to amblyopia. Invest. Ophthal. Vis. Sci. Vol 26, 1610-1623, 1985.
– reference: 12) G. E. Holder: Significance of abnormal pattern electroretinography in anterior visual pathway dysfunction. Bri. J. Ophthal. 71, 166-171, 1987.
– reference: 18) H. Ikeda: Visual acuity, its development and amblyopia. J. Royal Sosiety of Med. Vol 73, 546-555, 1980.
– reference: 6) I. Gottlob & L. Welge-Lussent: Nomal pattern electroretinogram in amblyopia. Invest. Ophthal. Vis. Sci. Vol 28, 187-191, 1987.
– reference: 9) L. Maffei & A. Fiorentini: Electroretinographic responses to alternating gratings before and after section of the optic nerve. Science 211, 953-955, 1981.
– reference: 1) G. B. Arden, Vaegan et al: Pattern ERGs are abnormal in many amblyopes. Trans. Ophthal. Soc. U. K. 100, 453-460, 1980.
– reference: 16) 新井三樹, 直井信久他:Pattern ERG, VEPにおける測定誤差について. 臨眼80, 1751-1756, 1986.
– reference: 13) G. G. Celesia, D. Kaufman et al: Simaltaneuos recording of pattern electroretinography and visual evoked potentials in multiple sclerosis. A method to separate demyelination from axonal damage to the optic nerve. Arch. Neurology, 43, 1247-1252, 1986.
– reference: 17) 宮澤裕之, 関谷善文他:パターンERGの早期緑内障検出能力の検討. 日眼92, 156-160, 1988.
– reference: 19) H. Ikeda & K. E. Tremain: Amblyopia resulting from penalisation; neurophysiological studies of kittens reared with atropinisation of one or both eyes. Bri. J. Ophthal. 62, 21-28, 1978.
– reference: 5) H. E. Persson & P. Wanger: Pattern-reversal electroretinogram in squint amblyopia, artificial anisometropia and simulated eccentric fixation. Acta Ophthalmologica, 60, 123-132, 1982.
– reference: 4) P. Wanger & H. E. Persson: Oscillatory potentials, flash and pattern-reversal electroretinogram in amblyopia. Acta Ophthalmologica, 62, 143-650, 1984.
– reference: 3) G. B. Arden & S. L. Wooding: Pattern ERG in Amblyopia. Invest. Ophthal. Vis. Sci. Vol 26, 88-96, 1985.
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SubjectTerms ametropic amblyopia
anisometropic amblyopia
orthoptic treatment
pattern-reversal electoretinogram
strabismic amblyopia
Title A TRIAL OF P-ERG FOR THE AID OF THERAPY IN AMBLYOPIA (2)
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