Infliximab for treating sarcoidosis patients, Portuguese experience

• Published in: Revista portuguesa de pneumologia (English ed.) Vol. 17; no. 2; pp. 85 - 93
• Main Authors: Aguiar, M, Marçal, N, Mendes, A.C, Bugalho de Almeida, A
• Format: Journal Article
• Language: English
• Published: Elsevier España 01.03.2011
• Subjects: Infl iximab; Internal Medicine; Pulmonary/Respiratory; Sarcoidose; Sarcoidosis; Infl iximab; Sarcoidosis; Sarcoidose

Abstract Despite aggressive treatment, sarcoidosis may be debilitating and progressive. The role of tumor necrosis factor (TNF) ap in the genesis of granulomas is ambiguous. It has proved to be critical in the formation and maintenance of granulomatous inflammation and its antagonist, Infl iximab, h...