An alkaloid from Menispermum dauricum, dauricine mediates Ca2+ influx and inhibits NF-κB pathway to protect chondrocytes from IL-1β-induced inflammation and catabolism

ETHNOPHARMACOLOGICAL RELEVANCEDauricine (DA) is a natural plant-derived alkaloid extracted from Menispermum dauricum. Menispermum dauricum has been used in traditional Chinese medicine as a classic remedy for rheumatoid arthropathy and is believed to be effective in alleviating swelling and pain in...

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Bibliographic Details
Published inJournal of ethnopharmacology Vol. 321; p. 117560
Main Authors Xia, Gan-Qing, Zhu, Mei-Peng, Li, Jian-Wen, Huang, Hui
Format Journal Article
LanguageEnglish
Published 01.03.2024
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