Is there room for luminal-basal urothelial cell population quantification?

• Published in: Actas urologicas españolas Vol. 41; no. 8; pp. 504 - 510
• Main Authors: Passos, G.R., Camargo, J.A., Ferrari, K.L., Franch, G.C., Nowill, A.E., Reis, L.O.
• Format: Journal Article
• Language: English
• Published: Spain Elsevier España 01.10.2017
• Subjects: Animals; Basal; Cell Count; Cell Separation - methods; Collagenases; Epithelial Cells - classification; Epithelial Cells - ultrastructure; Flow Cytometry; Intermediate; Intermedio; Luminal; Male; Peptide Hydrolases; Prognostic; Pronóstico; Random Allocation; Rats; Specimen Handling - methods; Urotelio; Urothelium; Urothelium - cytology; Basal; Pronóstico; Intermediate; Luminal; Intermedio; Urotelio; Prognostic; Urothelium

Three cell layers compose the urothelium: basal, intermediate and luminal (“umbrella cells”) and different diseases might arise from different cell populations. The aim of this study is to analyze the quantification ability of such cell populations by using four different protocols. Twenty male rats...