Expression of glycogenes in differentiating human NT2N neurons. Downregulation of fucosyltransferase 9 leads to decreased Lewisx levels and impaired neurite outgrowth - Gouveia, Ricardo; Schaffer, Lana; Papp, Suzanne; Grammel, Nicolas; Kandzia, Sebastian; Head, Steven R.; Kleene, Ralf; Schachner, Melitta; Conradt, Harald S.; Costa, Júlia (Biochimica et biophysica acta. General subjects, 2012)
Keywords: carbohydrates; cell adhesion; cells; Central nervous system; epitopes; fluorescence microscopy; Fucosyltransferase 9; genes; glycoproteins; glycosylation; high performance liquid chromatography; HPLC; humans; immunofluorescence; Lewisx; messenger RNA; microarray technology; microscopy; Neurite outgrowth; Neuron glycosylation; Neuronal differentiation; neurons; peptides; precipitin tests; proteins; regulations; RNA interference; PBS; TBS; HRP; Lewisx; PNGase F; HPAEC-PAD; EDTA; EGTA; BSA; MALDI-TOF MS; SDS-PAGE; HNK-1; Gal; Fuc; HexNAc; Neuronal differentiation; dHex; Fucosyltransferase 9; GlcNAc; Hex; Man; Neuron glycosylation; Lex; Neurite outgrowth