Effects of Cnidium monnieri (L.) Cuss. fruit extract on sexual behaviors in male rats

Background Cnidium monnieri (L.) Cuss. has been used for a long time according to the traditional experiences and documentation in order to treat male sexual disorders. Osthole is one of the main bioactive components in Cnidium monnieri (L.) Cuss . In this study, we aimed to evaluate the effect of C...

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Published inClinical phytoscience Vol. 6; no. 1
Main Authors Dau, Thuy Duong, Le, Minh Ha, Nguyen, Tran Thi Giang Huong, Dang, Thi Ngoc Mai, Do, Thi Nguyet Que, Tran, Quynh Trang
Format Journal Article
LanguageEnglish
Published Berlin/Heidelberg Springer Berlin Heidelberg 25.11.2020
Springer Nature B.V
Subjects
Cnidium monnieri
Diabetes
Disorders
Fruits
Gastroenterology
Gynecology
High-performance liquid chromatography
Latency
Liquid chromatography
Medicine
Medicine & Public Health
Oral administration
Original Contribution
Pediatrics
Pneumology/Respiratory System
Rodents
Sexual behavior
Rats
Male sexual disorders
Osthole
Sexual behaviors
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Abstract Background Cnidium monnieri (L.) Cuss. has been used for a long time according to the traditional experiences and documentation in order to treat male sexual disorders. Osthole is one of the main bioactive components in Cnidium monnieri (L.) Cuss . In this study, we aimed to evaluate the effect of Cnidium monnieri (L.) Cuss. fruit extract of which osthole content was 35% (determined by HPLC method) on sexual behaviors in adult male rats. Methods Cnidium monnieri (L.) Cuss. fruit extract was administered orally at the dose of 150 mg/kg b.w and after 30 min, male rats were coupled with receptive adult female rats to evaluate sexual behaviors, including mounting and intromission. Results Cnidium monnieri (L.) Cuss. fruit extract at the dose of 150 mg/kg b.w increased the percentage of rats that mounted and intromitted; increased the intromission frequency and decreased mounting latency and intromission latency. Conclusion Cnidium monnieri (L.) Cuss. fruit extract increased the ability to mount and intromit in rats, and scientifically support the traditional use of Cnidium monnieri (L.) Cuss. in treatment of male sexual disorders.
AbstractList Abstract Background Cnidium monnieri (L.) Cuss. has been used for a long time according to the traditional experiences and documentation in order to treat male sexual disorders. Osthole is one of the main bioactive components in Cnidium monnieri (L.) Cuss . In this study, we aimed to evaluate the effect of Cnidium monnieri (L.) Cuss. fruit extract of which osthole content was 35% (determined by HPLC method) on sexual behaviors in adult male rats. Methods Cnidium monnieri (L.) Cuss. fruit extract was administered orally at the dose of 150 mg/kg b.w and after 30 min, male rats were coupled with receptive adult female rats to evaluate sexual behaviors, including mounting and intromission. Results Cnidium monnieri (L.) Cuss. fruit extract at the dose of 150 mg/kg b.w increased the percentage of rats that mounted and intromitted; increased the intromission frequency and decreased mounting latency and intromission latency. Conclusion Cnidium monnieri (L.) Cuss. fruit extract increased the ability to mount and intromit in rats, and scientifically support the traditional use of Cnidium monnieri (L.) Cuss. in treatment of male sexual disorders.
BackgroundCnidium monnieri (L.) Cuss. has been used for a long time according to the traditional experiences and documentation in order to treat male sexual disorders. Osthole is one of the main bioactive components in Cnidium monnieri (L.) Cuss. In this study, we aimed to evaluate the effect of Cnidium monnieri (L.) Cuss. fruit extract of which osthole content was 35% (determined by HPLC method) on sexual behaviors in adult male rats.MethodsCnidium monnieri (L.) Cuss. fruit extract was administered orally at the dose of 150 mg/kg b.w and after 30 min, male rats were coupled with receptive adult female rats to evaluate sexual behaviors, including mounting and intromission.ResultsCnidium monnieri (L.) Cuss. fruit extract at the dose of 150 mg/kg b.w increased the percentage of rats that mounted and intromitted; increased the intromission frequency and decreased mounting latency and intromission latency.ConclusionCnidium monnieri (L.) Cuss. fruit extract increased the ability to mount and intromit in rats, and scientifically support the traditional use of Cnidium monnieri (L.) Cuss. in treatment of male sexual disorders.
Background Cnidium monnieri (L.) Cuss. has been used for a long time according to the traditional experiences and documentation in order to treat male sexual disorders. Osthole is one of the main bioactive components in Cnidium monnieri (L.) Cuss . In this study, we aimed to evaluate the effect of Cnidium monnieri (L.) Cuss. fruit extract of which osthole content was 35% (determined by HPLC method) on sexual behaviors in adult male rats. Methods Cnidium monnieri (L.) Cuss. fruit extract was administered orally at the dose of 150 mg/kg b.w and after 30 min, male rats were coupled with receptive adult female rats to evaluate sexual behaviors, including mounting and intromission. Results Cnidium monnieri (L.) Cuss. fruit extract at the dose of 150 mg/kg b.w increased the percentage of rats that mounted and intromitted; increased the intromission frequency and decreased mounting latency and intromission latency. Conclusion Cnidium monnieri (L.) Cuss. fruit extract increased the ability to mount and intromit in rats, and scientifically support the traditional use of Cnidium monnieri (L.) Cuss. in treatment of male sexual disorders.
ArticleNumber 80
Author Dang, Thi Ngoc Mai
Do, Thi Nguyet Que
Nguyen, Tran Thi Giang Huong
Tran, Quynh Trang
Le, Minh Ha
Dau, Thuy Duong
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  organization: Department of Pharmacology, Hanoi Medical University
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Issue 1
Keywords Rats
Male sexual disorders
Osthole
Sexual behaviors
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Snippet Background Cnidium monnieri (L.) Cuss. has been used for a long time according to the traditional experiences and documentation in order to treat male sexual...
Abstract Background Cnidium monnieri (L.) Cuss. has been used for a long time according to the traditional experiences and documentation in order to treat male...
BackgroundCnidium monnieri (L.) Cuss. has been used for a long time according to the traditional experiences and documentation in order to treat male sexual...
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SubjectTerms Cnidium monnieri
Diabetes
Disorders
Fruits
Gastroenterology
Gynecology
High-performance liquid chromatography
Latency
Liquid chromatography
Medicine
Medicine & Public Health
Oral administration
Original Contribution
Pediatrics
Pneumology/Respiratory System
Rodents
Sexual behavior
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Title Effects of Cnidium monnieri (L.) Cuss. fruit extract on sexual behaviors in male rats
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