Severe Focal Sialadenitis and Dacryoadenitis in NZM2328 Mice Induced by MCMV: A Novel Model for Human Sjögren’s Syndrome

• Published in: The Journal of immunology (1950) Vol. 177; no. 10; pp. 7391 - 7397
• Main Authors: Ohyama, Yukiko, Carroll, Virginia A., Deshmukh, Umesh, Gaskin, Felicia, Brown, Michael G., Fu, Shu Man
• Format: Journal Article
• Language: English; Japanese
• Published: 15.11.2006

The genetic and environmental factors that control the development of Sjögren’s syndrome, an autoimmune disease mainly involving the salivary and lacrimal glands, are poorly understood. Viruses which infect the glands may act as a trigger for disease. The ability of sialotropic murine CMV (MCMV) to...