Aptamer‐Mediated Artificial Synapses for Neuromorphic Modulation of Inflammatory Signaling via Organic Electrochemical Transistor

• Published in: Advanced science p. e09545
• Main Authors: Ding, Yuqing, Kuai, You, Li, Rongpei, Xu, Xinzhao, Wang, Bo, Wang, Zhihui, Liu, Yanfang, Dong, Yuchao, Chen, Shunjie, Guo, Meng, Liu, Yunqi, Zhao, Yan
• Format: Journal Article
• Language: English
• Published: Germany 04.08.2025
• Subjects: neuromorphic interface; synaptic plasticity; interleukin‐6 sensing; aptamer‐based biosensor; organic electrochemical transistor

Artificial synaptic devices that mimic neuromorphic signal processing hold great promise for bioelectronic interfaces. However, most systems remain limited to physical stimuli or electroactive small molecules, lacking the ability to transduce biologically relevant protein signals. To address this li...