Use of lectins as vector molecules for delivery of drugs to cells and tissues. Report 2

• Published in: Biopolimery i kletka Vol. 35; no. 1; pp. 54 - 63
• Main Authors: Antonyuk, V. O., Skorohyd, N. R., Lozynskyi, A. V., Antonyuk, R. V., Lesyk, R. B., Stoika, R. S.
• Format: Journal Article
• Language: English
• Published: Kiev Natsional'na Akademiya Nauk Ukrainy - National Academy of Sciences of Ukraine 2019
• Subjects: Bioactive compounds; Biological activity; Cell culture; Cytotoxicity; Drug delivery; Human serum albumin; Lectins; Nuts; Seeds; Tumor cells

Aim.To determine cytotoxic effects towards a tumor cells culture of the heterocyclic derivative conjugated with lectins of different carbohydrate specificity. Methods. Conjugation of lectins (Pea seeds (PSA), peanuts (PNA) and erythroagglyutinin from bean seeds (PHA-E) with thiopyrano[2,3-d]thiazole...