Mesenchymal Stem Cells Treatment Aggravates Tumor Growth Regardless Its Route of Administration: An In vivo Study

• Published in: Asian Pacific journal of cancer prevention : APJCP Vol. 23; no. 10; pp. 3309 - 3315
• Main Authors: Mostafa, Abeer, Mohamed Abdelsalam, Shimaa, S Sabbah, W, Mekawey, Dina
• Format: Journal Article
• Language: English
• Published: Thailand West Asia Organization for Cancer Prevention 01.10.2022
• Subjects: Animals; Cytokines - metabolism; Female; Matrix Metalloproteinase 2 - metabolism; Mesenchymal Stem Cell Transplantation; Mesenchymal Stem Cells; Mice; Rats; RNA, Long Noncoding - metabolism; Erlish; MSCs; MMP2 and TNF; lncRNA MALAT

to clarify the effect of MSCs in cancer growth and to detect whether the rout of administration (either locally inside the tumor tissue or systemic )could affect the outcome of treatment or not. Eighteen female mice were involved in the study. All mice were subcutaneously inoculated with Ehrlich tum...