A Case Report of Heterotopic Gray Matter
A case of heterotopic gray matter in the left subependymal region is reported. The patient was a 16 year-old female who was admitted to the Department of Neurosurgery on March 10, 1978 with chief complaints of syncope and generalized convulsion. Neurological examination on admission revealed no abno...
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Published in | Neurologia medico-chirurgica Vol. 20; no. 10; pp. 1049 - 1054 |
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Main Authors | , , , |
Format | Journal Article |
Language | English |
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The Japan Neurosurgical Society
1980
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Abstract | A case of heterotopic gray matter in the left subependymal region is reported. The patient was a 16 year-old female who was admitted to the Department of Neurosurgery on March 10, 1978 with chief complaints of syncope and generalized convulsion. Neurological examination on admission revealed no abnormalities. CT scan showed a broad-based isodense mass in the dilated left lateral ventricle, which was not enhanced by contrast media. Pneumoencephalography revealed a round defect in the center of the left lateral ventricle. On April 12, 1978, the left lateral ventricle was entered through a corticotomy, and a round lump covered by ependymal wall was discovered at the posterior part of the foramen of Monro. This bulging mass was completely removed. CT Scan after surgery showed that no mass remained. Histopathologically, cells were noted and mild gliosis and some scattered neuron. This specimen was regarded as a gray matter. No malignancy was identified. Postoperatively, she was free from any convulsions or syncope. In this case, CT scan was a useful diagnostic procedure among other neuroradiological studies for differential diagnosis. |
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AbstractList | A case of heterotopic gray matter in the left subependymal region is reported. The patient was a 16 year-old female who was admitted to the Department of Neurosurgery on March 10, 1978 with chief complaints of syncope and generalized convulsion. Neurological examination on admission revealed no abnormalities. CT scan showed a broad-based isodense mass in the dilated left lateral ventricle, which was not enhanced by contrast media. Pneumoencephalography revealed a round defect in the center of the left lateral ventricle. On April 12, 1978, the left lateral ventricle was entered through a corticotomy, and a round lump covered by ependymal wall was discovered at the posterior part of the foramen of Monro. This bulging mass was completely removed. CT Scan after surgery showed that no mass remained. Histopathologically, cells were noted and mild gliosis and some scattered neuron. This specimen was regarded as a gray matter. No malignancy was identified. Postoperatively, she was free from any convulsions or syncope. In this case, CT scan was a useful diagnostic procedure among other neuroradiological studies for differential diagnosis. |
Author | KONDO, TAKASHI KANO, MITSUMASA TAKIMOTO, NOBORU USHIO, YUKITAKA |
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References | 10) MALAMUD, N. & HIRANO, A.: Atlas of neuropathology. ch. x. Developmental disorders. 2nd ed. Univ. of California Press, London, 1974 9) KERNOHAN, J. W.: Cortical anomalies, ventricular heterotopias and occlusions of aqueduct of Sylvius. Arch Neurol Psychiat 23: 460-480, 1930 6) DENNIS, J. & BOWER, B. D.: The Aicardi syndrome. Dev Med Child Neurol 14: 382-390, 1972 2) BERTONI, J. M., SIEGRUM VON LOH, & ALLEN, R. D.: The Aicardi syndrome; report of 4 cases and review of the literature. Ann Neurol 5: 475 482, 1979 4) COWEN, D. & GELLER, L. M.: Long-term pathological effects of prenatal x-irradiation on the central nervous system of the rat. J Neuro pathol Exp Neurol 19: 488-527, 1960 13) MUELLER, C. F.: Heterotopic gray matter. Radiology 94: 357-358, 1970 3) BOESEL, C. P., PAULSON, G. W., KOSNIK, E. J. & EARLE, K. M.: Brain hamartomas and tumors associated with tuberous sclerosis. Neuro surgery 4: 410-417, 1979 14) TAYLOR, D. C., FALCONER, M. A., BRUTON, C. J. & CORSELLIS, J. A. N.: Focal dysplasia of the cerebral cortex in epilepsy. J Neurol Neuro surg Psychiatry 34: 369-387, 1971 11) 間中信也, 佐藤誠太郎, 淵之上徳郎, 関野宏明,永井政勝, 佐野圭司 : Uncontrollable epilepsyの原因となったEctopic Gray Matterの一治験例. 脳神経24 : 311-318, 1972 5) DAVIDOFF, L. M. & DYKE, G. A.: Agenesis of the corpus callosum; Diagnosis by encephalog raphy, reports of 3 cases. Am J Roentgenol 32: 1-10, 1934 1) BERGERON, R. T.: Pneumographic demonstration of subependymal heterotopic cortical gray matter in childern. AJR 101: 168-177, 1967 7) JEANNETTE, J. T., NIELSEN, S. L. & MALAMUD, N.: Unilateral megalencephaly; Hamartoma or neoplasm? Neurology 25: 448-459, 1975 12) MIKHAEL, M. A. & MATTER, A. G.: Malformation of the cerebral cortex with heterotopia of the gray matter. J Comput Assist Tomography 2 (3): 291-296, 1978 8) KENDALL, B. E. & KINGSLEY, D.: The value of computerized tomography (CAT) in cranio-cerebral malformations. Br J Radiol 51: 171-190, 1978 15) VINKEN, P. J., BRUYN G. W. edi.: Handbook of Clinical Neurology. Vol. 30, Congenital malformations of the brain and skull. ch. 19, Cytoarchitectonic abnormalities. North-Holland Publishing Com., Amsterdam, 1977 |
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