A case of hepatocellular carcinoma relapsed 44 months after living donor liver transplantation, with a 50-month survival thereafter by multimodal treatments
Here we report a case of 34 years old female with chronic hepatitis B, who had undergone extended left lobectomy for a huge hepatocellular carcinoma (HCC) with a diameter of 12 cm when she was 25 years old. The HCC recurred in the following year, and a living donor liver transplantation (LDLT) was p...
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| Published in | Kanzo Vol. 50; no. 4; pp. 192 - 200 |
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| Main Authors | , , , , , , , , , , , |
| Format | Journal Article |
| Language | Japanese |
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The Japan Society of Hepatology
2009
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| Abstract | Here we report a case of 34 years old female with chronic hepatitis B, who had undergone extended left lobectomy for a huge hepatocellular carcinoma (HCC) with a diameter of 12 cm when she was 25 years old. The HCC recurred in the following year, and a living donor liver transplantation (LDLT) was performed at 27 years of age. Recurrent tumors were revealed in the graft at 44 months after LDLT. Though percutaneous treatments were done repeatedly, many uncontrollable tumors appeared in succession. Posterior-segmentectomy and partial resection of anterior-segment were performed at 32 years of age. Recurrent tumors appeared one after another despite those intensive therapies, and the patient expired 94 months after LDLT; 50 months after the post-LDLT recurrence. To our knowledge, this is the first case of recurrent HCCs appearing more than 3 years after LDLT and then undergoing a graft segmentectomy. |
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| AbstractList | Here we report a case of 34 years old female with chronic hepatitis B, who had undergone extended left lobectomy for a huge hepatocellular carcinoma (HCC) with a diameter of 12 cm when she was 25 years old. The HCC recurred in the following year, and a living donor liver transplantation (LDLT) was performed at 27 years of age. Recurrent tumors were revealed in the graft at 44 months after LDLT. Though percutaneous treatments were done repeatedly, many uncontrollable tumors appeared in succession. Posterior-segmentectomy and partial resection of anterior-segment were performed at 32 years of age. Recurrent tumors appeared one after another despite those intensive therapies, and the patient expired 94 months after LDLT; 50 months after the post-LDLT recurrence. To our knowledge, this is the first case of recurrent HCCs appearing more than 3 years after LDLT and then undergoing a graft segmentectomy. |
| Author | Inoue, Takeshi Nakai, Takashi Horii, Katsuhiko Oka, Hiroko Kioka, Kiyohide Kawasaki, Yasuko Kanazawa, Akishige Murata, Katsuko Manabe, Takao Kouda, Youichi Shimizu, Sadatoshi Yamazaki, Osamu |
| Author_xml | – sequence: 1 fullname: Oka, Hiroko organization: Department of Gastroenterology, Osaka City General Hospital – sequence: 2 fullname: Yamazaki, Osamu organization: Department of Surgery, Osaka City General Hospital – sequence: 3 fullname: Horii, Katsuhiko organization: Department of Surgery, Osaka City General Hospital – sequence: 4 fullname: Manabe, Takao organization: Department of Radiology, Osaka City General Hospital – sequence: 5 fullname: Kioka, Kiyohide organization: Department of Gastroenterology, Osaka City General Hospital – sequence: 6 fullname: Kawasaki, Yasuko organization: Department of Gastroenterology, Osaka City General Hospital – sequence: 7 fullname: Nakai, Takashi organization: Department of Gastroenterology, Osaka City General Hospital – sequence: 8 fullname: Kanazawa, Akishige organization: Department of Surgery, Osaka City General Hospital – sequence: 9 fullname: Shimizu, Sadatoshi organization: Department of Surgery, Osaka City General Hospital – sequence: 10 fullname: Murata, Katsuko organization: Department of Radiology, Osaka City General Hospital – sequence: 11 fullname: Kouda, Youichi organization: Department of Radiology, Osaka City General Hospital – sequence: 12 fullname: Inoue, Takeshi organization: Department of Pathology, Osaka City General Hospital |
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| Cites_doi | 10.1200/JCO.1999.17.1.324 10.1097/01.sla.0000137129.98894.42 10.1002/lt.21189 10.1002/lt.20128 10.1002/lt.21445 10.1111/j.1432-2277.2006.00338.x 10.1097/01.tp.0000259015.46798.ec 10.1002/lt.20549 10.2957/kanzo.44.546 10.1002/lt.21281 10.1053/jlts.2002.34922 10.1053/jhep.2001.24563 10.1046/j.1440-1746.2001.02643.x 10.1159/000106910 10.1056/NEJM199603143341104 10.1007/PL00009947 10.1002/lt.21334 10.1002/lt.20642 10.1097/01.sla.0000109022.32391.eb 10.1097/01.TP.0000047029.02806.16 10.1016/j.transproceed.2004.12.030 10.1148/radiology.218.3.r01mr39763 10.2957/kanzo.44.632 |
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| Title | A case of hepatocellular carcinoma relapsed 44 months after living donor liver transplantation, with a 50-month survival thereafter by multimodal treatments |
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