Evaluation of xanthine oxidase inhibitory activity of sinapyl alcohol diacetate and stigmasterol compounds and phytochemical screening stem of Etlingera rubroloba A.D Poulsen

• Published in: Food Research (Online) Vol. 7; no. 4; pp. 101 - 105
• Main Authors: Jabbar, A., Sahidin, I., Malik, F., Ilyas, M.Y., Rusli, N., Reymon, Qadar, J.
• Format: Journal Article
• Language: English
• Published: 11.08.2023
• DOI: 10.26656/fr.2017.7(4).009
• ISSN: 2550-2166

Etlingera rubroloba A.D Poulsen is a genus Etlingera found in Southeast Sulawesi. This plant is widely used in local communities to relieve joint pain and increase stamina. Previous researchers isolated and identified this plant to obtain the compounds sinapyl alcohol diacetate and stigmasterol. However, these two compounds have never been reported on the Xanthine Oxidase (XO) inhibitory activity in vitro. The results of phytochemical screening have also not been reported in this plant. Therefore, in this study, a phytochemical screening test was conducted using colour reagents, and an in vitro test for XO inhibitory activity was carried out using the XO Kit. The results showed that E. rubroloba contains secondary metabolites of flavonoids, alkaloids, tannins, saponins, terpenoids, and the value of the percent XO inhibitory activity at a concentration of 320 µg/mL, namely sinapyl alcohol diacetate 85.52%, stigmasterol 90.42%, and allopurinol 97.63%, as a positive control. This research will be a reference in the development of antihyperuricemia medicine of nature.