The Spectrum Of Pathological Findings Of Kidney Injury In The Cases Of Multiple Myeloma: A Clinico-Pathological Study Of 93 Consecutive Autopsy Cases

• Published in: Blood Vol. 122; no. 21; p. 5321
• Main Authors: Mine, Sohtaro, Hagiwara, Shotaro, Hirai, Risen, Tanimura, Akira, Nakamura, Miki, Takeshita, Masataka, Miwa, Akiyoshi, Igari, Toru
• Format: Journal Article
• Language: English; Japanese
• Published: Elsevier Inc 15.11.2013; American Society of Hematology

Kidney injury and/or renal failure are common complication in multiple myeloma. Well known mechanism is deposition of free immunoglobulin light chains in renal tubules leading to cast nephropathy and renal failure. In addition, not only cast nephropathy, but also invasion of myeloma cells is frequen...