PGE 2 -EP3 signaling pathway impairs hippocampal presynaptic long-term plasticity in a mouse model of Alzheimer's disease
Alzheimer's disease (AD) is a progressive neurodegenerative disease characterized by early cognitive deficits linked to synaptic dysfunction and loss. Considerable evidence suggests that neuroinflammation contributes to AD. Prostaglandin E (PGE ), a key neuroinflammatory molecule, modulates hip...
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Published in | Neurobiology of aging Vol. 50; pp. 13 - 24 |
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Main Authors | , , , , , |
Format | Journal Article |
Language | English |
Published |
United States
01.02.2017
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Subjects | |
Online Access | Get full text |
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