Monitoring of metabolism perturbation in prostate PC-3 cancer cells by sub-lethal concentrations of methotrexate

• Published in: Spectroscopy Vol. 24; no. 1-2; pp. 55 - 60
• Main Authors: Derenne, Allison, Gasper, Régis, Goormaghtigh, Erik
• Format: Journal Article
• Language: English
• Published: 2010

Infrared imaging was used to investigate the effect of sub-lethal concentration of methotrexate on prostate PC-3 cancer cells. Cells were exposed for 0, 24 and 48 h to 9 nM of methotrexate, the concentration that inhibits 50% of cell growth after 72 h. Sub-lethal concentrations of methotrexate induc...