Cohorte MecoExpo : utilisation du méconium pour estimer l’exposition in utero aux pesticides des nouveau-nés en Picardie

Résumé Objectif L’étude MecoExpo menée en Picardie, région agricole utilisatrice de pesticides, visait à mettre en relation l’exposition parentale et l’imprégnation foetale aux pesticides avec les paramètres cliniques du développement fœtal relevés à la naissance. Matériel et méthode L’exposition pa...

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Published inRevue de médecine périnatale Vol. 6; no. 2; pp. 122 - 133
Main Authors Tourneux, P., Mayhoub, F., Haraux, E., Deguines, C., Berton, T., Lestremeau, F., Gondry, J., Bach, V., Chardon, K.
Format Journal Article
LanguageFrench
Published Paris Springer Paris 2014
Springer
Springer Link
Subjects
Article Original
Critical Care Medicine
Divers
Environmental Sciences
Generalites
Imaging
Intensive
Medicine
Medicine & Public Health
Obstetrics/Perinatology/Midwifery
Original Article
Pediatrics
Radiology
Sante publique. Hygiene-medecine du travail
Santé publique. Hygiène
Sciences biologiques et medicales
Sciences medicales
France
Picardie
Europe
Exposition in utéro
Pesticides
Environmental health
Santé-environnement
Infant
Pronostic
Nouveau-né
Adverse effects
In utero exposure
Fœtus
Newborn
Outcome
Fetus
Effets indésirables
Estimation
Foetus
Gestation
In utero
Exposition
Homme
Pesticide
Toxicité
Nourrisson
Santé publique
Utilisation
Environnement
Etude cohorte
Méconium
Nouveau né
PRONOSTIC
NEWBORN
OUTCOME
ENVIRONMENTAL HEALTH
FETUS
EFFETS INDESIRABLES
EXPOSITION IN UTERO
PESTICIDES
NOUVEAU-NE
IN UTERO EXPOSURE
INFANT
FOETUS
SANTE-ENVIRONNEMENT
ADVERSE EFFECTS
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Abstract Résumé Objectif L’étude MecoExpo menée en Picardie, région agricole utilisatrice de pesticides, visait à mettre en relation l’exposition parentale et l’imprégnation foetale aux pesticides avec les paramètres cliniques du développement fœtal relevés à la naissance. Matériel et méthode L’exposition parentale aux pesticides a été évaluée par un questionnaire et l’imprégnation foetale aux pesticides, pour la première fois en France, par un dosage dans le méconium. Résultats Neuf cent quatre-vingt-treize couples mère-enfant ont été inclus. Une association entre exposition professionnelle maternelle aux pesticides et augmentation du risque de restriction de croissance fœtale pour le poids de naissance a été observée. Une augmentation du risque de prématurité chez les enfants issus de père travaillant dans un secteur exposé aux pesticides a également été relevée. Quatre-vingt-cinq pour cent des nouveau-nés présentaient au moins un des pesticides recherchés dans leur méconium. Les pesticides observés le plus fréquemment sont les métabolites des organophosphorés et ceux des carbamates, deux grandes familles d’insecticides dispersés sur les grandes cultures. Conclusion Des associations entre l’exposition professionnelle maternelle et paternelle et les paramètres cliniques à la naissance ont été observées. La recherche des pesticides a été réalisée pour la première fois en France dans le méconium de nouveau-nés.
AbstractList Résumé Objectif L’étude MecoExpo menée en Picardie, région agricole utilisatrice de pesticides, visait à mettre en relation l’exposition parentale et l’imprégnation foetale aux pesticides avec les paramètres cliniques du développement fœtal relevés à la naissance. Matériel et méthode L’exposition parentale aux pesticides a été évaluée par un questionnaire et l’imprégnation foetale aux pesticides, pour la première fois en France, par un dosage dans le méconium. Résultats Neuf cent quatre-vingt-treize couples mère-enfant ont été inclus. Une association entre exposition professionnelle maternelle aux pesticides et augmentation du risque de restriction de croissance fœtale pour le poids de naissance a été observée. Une augmentation du risque de prématurité chez les enfants issus de père travaillant dans un secteur exposé aux pesticides a également été relevée. Quatre-vingt-cinq pour cent des nouveau-nés présentaient au moins un des pesticides recherchés dans leur méconium. Les pesticides observés le plus fréquemment sont les métabolites des organophosphorés et ceux des carbamates, deux grandes familles d’insecticides dispersés sur les grandes cultures. Conclusion Des associations entre l’exposition professionnelle maternelle et paternelle et les paramètres cliniques à la naissance ont été observées. La recherche des pesticides a été réalisée pour la première fois en France dans le méconium de nouveau-nés.
The MecoExpo study was conducted in Picardy, an agricultural region where pesticides are used. This study was designed to evaluate the relationship between parental and fetal exposure to pesticides. Neonatal anthropomorphic parameters were compared to parental pesticide exposure during pregnancy. Parental exposure to pesticides was assessed by means of a validated questionnaire. In utero fetal exposure was assessed for the first time in France by means of neonatal meconium assays. Nine-hundred and ninety-three mother-newborn pairs were included. A significant relationship was observed between maternal occupational exposure to pesticides and low birth weight for gestational age. An association was also observed between preterm birth and paternal exposure to pesticides. At least one pesticide was detected on meconium screening in 85% of newborns. The pesticides most frequently detected were organophosphorus and carbamate metabolites. These pesticides are commonly used for extensive field treatments in Picardy. A significant relationship was observed between maternal and paternal occupational exposure to pesticides and neonatal anthropomorphic parameters. Positive screening for pesticides in the meconium of newborns was assessed for the first time in France. L’étude MecoExpo menée en Picardie, région agricole utilisatrice de pesticides, visait à mettre en relation l’exposition parentale et l’imprégnation foetale aux pesticides avec les paramètres cliniques du développement fœtal relevés à la naissance. L’exposition parentale aux pesticides a été évaluée par un questionnaire et l’imprégnation foetale aux pesticides, pour la première fois en France, par un dosage dans le méconium. Neuf cent quatre-vingt-treize couples mère-enfant ont été inclus. Une association entre exposition professionnelle maternelle aux pesticides et augmentation du risque de restriction de croissance fœtale pour le poids de naissance a été observée. Une augmentation du risque de prématurité chez les enfants issus de père travaillant dans un secteur exposé aux pesticides a également été relevée. Quatre-vingt-cinq pour cent des nouveau-nés présentaient au moins un des pesticides recherchés dans leur méconium. Les pesticides observés le plus fréquemment sont les métabolites des organophosphorés et ceux des carbamates, deux grandes familles d’insecticides dispersés sur les grandes cultures. Des associations entre l’exposition professionnelle maternelle et paternelle et les paramètres cliniques à la naissance ont été observées. La recherche des pesticides a été réalisée pour la première fois en France dans le méconium de nouveau-nés.
Author Mayhoub, F.
Chardon, K.
Haraux, E.
Berton, T.
Bach, V.
Deguines, C.
Lestremeau, F.
Gondry, J.
Tourneux, P.
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Cites_doi 10.2478/v10001-008-0014-z
10.1006/eesa.2001.2110
10.1289/ehp.7769
10.1186/1476-069X-10-79
10.1007/BF01683575
10.1016/S0166-4328(97)00181-2
10.1097/EDE.0b013e318187cc5d
10.2105/AJPH.84.5.731
10.1289/ehp.6414
10.1542/peds.2005-1781
10.1016/S0022-3476(94)70379-5
10.1289/ehp.0800041
10.1365/s10337-005-0668-7
10.1016/j.envres.2007.08.014
10.1016/j.taap.2004.11.027
10.1016/j.neuro.2004.10.004
10.1093/aje/kwr422
10.1080/00498250902745090
10.1007/s00431-005-0045-4
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Issue 2
Keywords Exposition in utéro
Pesticides
Environmental health
Santé-environnement
Infant
Pronostic
Nouveau-né
Adverse effects
In utero exposure
Fœtus
Newborn
Outcome
Fetus
Effets indésirables
Estimation
Foetus
Gestation
In utero
Exposition
Homme
Pesticide
Toxicité
Nourrisson
Santé publique
Utilisation
Environnement
Etude cohorte
Méconium
Nouveau né
PRONOSTIC
NEWBORN
OUTCOME
ENVIRONMENTAL HEALTH
FETUS
EFFETS INDESIRABLES
EXPOSITION IN UTERO
PESTICIDES
NOUVEAU-NE
IN UTERO EXPOSURE
INFANT
FOETUS
SANTE-ENVIRONNEMENT
ADVERSE EFFECTS
Language French
License CC BY 4.0
Distributed under a Creative Commons Attribution 4.0 International License: http://creativecommons.org/licenses/by/4.0
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PublicationTitle Revue de médecine périnatale
PublicationTitleAbbrev Rev. med. perinat
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References Petit, Blangiardo, Richardson (CR17) 2012; 175
Young, Eskenazi, Gladstone (CR7) 2005; 26
Grandjean, Harari, Barr, Debes (CR3) 2006; 117
Holene, Nafstad, Skaare, Sagvolden (CR5) 1998; 94
Bradman, Whyatt (CR2) 2005; 113
Bielawski, Ostrea, Posecion (CR21) 2005; 62
Whyatt, Camann, Perera (CR19) 2005; 206
Whyatt, Garfinkel, Hoepner (CR20) 2009; 117
Ostrea, Bielawski, Posecion (CR11) 2008; 106
Savitz, Whelan, Kleckner (CR15) 1989; 104
Berton, Mayhoub, Chardon (CR13) 2013
Mamelle, Boniol, Rivière (CR14) 2006; 165
Rosenstein, Chernoff (CR6) 1978; 20
Hong, Günter, Randow (CR9) 2002; 51
Steenland, Jenkins, Ames (CR1) 1994; 84
Jurewicz, Hanke (CR8) 2008; 21
Wohlfahrt-Veje, Main, Schmidt (CR16) 2011; 10
Berkowitz, Wetmur, Birman-Deych (CR18) 2004; 112
Handal, Harlow, Breilh, Lozoff (CR4) 2008; 19
Tsatsakis, Tzatzarakis, Koutroulakis (CR12) 2009; 39
Ostrea, Romero, Knapp (CR10) 1994; 124
C Wohlfahrt-Veje (277_CR16) 2011; 10
K Steenland (277_CR1) 1994; 84
P Grandjean (277_CR3) 2006; 117
EM Ostrea Jr (277_CR10) 1994; 124
DA Savitz (277_CR15) 1989; 104
JG Young (277_CR7) 2005; 26
J Jurewicz (277_CR8) 2008; 21
RM Whyatt (277_CR20) 2009; 117
L Rosenstein (277_CR6) 1978; 20
N Mamelle (277_CR14) 2006; 165
AM Tsatsakis (277_CR12) 2009; 39
A Bradman (277_CR2) 2005; 113
AJ Handal (277_CR4) 2008; 19
GS Berkowitz (277_CR18) 2004; 112
T Berton (277_CR13) 2013
RM Whyatt (277_CR19) 2005; 206
C Petit (277_CR17) 2012; 175
D Bielawski (277_CR21) 2005; 62
E Holene (277_CR5) 1998; 94
Z Hong (277_CR9) 2002; 51
EM Ostrea Jr (277_CR11) 2008; 106
References_xml – volume: 21
  start-page: 121
  year: 2008
  end-page: 132
  ident: CR8
  article-title: Prenatal and childhood exposure to pesticides and neurobehavioral development: review of epidemiological studies
  publication-title: Int J Occup Med Environ Health
  doi: 10.2478/v10001-008-0014-z
  contributor:
    fullname: Hanke
– volume: 51
  start-page: 60
  year: 2002
  end-page: 64
  ident: CR9
  article-title: Meconium: a matrix reflecting potential fetal exposure to organochlorine pesticides and its metabolites
  publication-title: Ecotoxicol Environ Saf
  doi: 10.1006/eesa.2001.2110
  contributor:
    fullname: Randow
– volume: 113
  start-page: 1092
  year: 2005
  end-page: 1099
  ident: CR2
  article-title: Characterizing exposures to nonpersistent pesticides during pregnancy and early childhood in the National Children’s Study: a review of monitoring and measurement methodologies
  publication-title: Environ Health Perspect
  doi: 10.1289/ehp.7769
  contributor:
    fullname: Whyatt
– year: 2013
  ident: CR13
  article-title: Development of an analytical strategy based on UPLC-MS/MS for the measurement of different classes of pesticides and theirs metabolites in meconium: application and characterisation of fetal exposure in France
  publication-title: Environ Res
  contributor:
    fullname: Chardon
– volume: 10
  start-page: 79
  year: 2011
  ident: CR16
  article-title: Lower birth weight and increased body fat at school age in children prenatally exposed to modern pesticides: a prospective study
  publication-title: Environ Health
  doi: 10.1186/1476-069X-10-79
  contributor:
    fullname: Schmidt
– volume: 20
  start-page: 624
  year: 1978
  end-page: 632
  ident: CR6
  article-title: Spontaneous and evoked EEG changes in perinatal rats following in utero exposure to Baygon: a preliminary investigation
  publication-title: Bull Environ Contam Toxicol
  doi: 10.1007/BF01683575
  contributor:
    fullname: Chernoff
– volume: 94
  start-page: 213
  year: 1998
  end-page: 224
  ident: CR5
  article-title: Behavioural hyperactivity in rats following postnatal exposure to sub-toxic doses of polychlorinated biphenyl congeners 153 and 126
  publication-title: Behav Brain Res
  doi: 10.1016/S0166-4328(97)00181-2
  contributor:
    fullname: Sagvolden
– volume: 19
  start-page: 851
  year: 2008
  end-page: 859
  ident: CR4
  article-title: Occupational exposure to pesticides during pregnancy and neurobehavioral development of infants and toddlers
  publication-title: Epidemiology
  doi: 10.1097/EDE.0b013e318187cc5d
  contributor:
    fullname: Lozoff
– volume: 84
  start-page: 731
  year: 1994
  end-page: 736
  ident: CR1
  article-title: Chronic neurological sequelae to organophosphate pesticide poisoning
  publication-title: Am J Public Health
  doi: 10.2105/AJPH.84.5.731
  contributor:
    fullname: Ames
– volume: 112
  start-page: 388
  year: 2004
  end-page: 391
  ident: CR18
  article-title: In utero pesticide exposure, maternal paraoxonase activity, and head circumference
  publication-title: Environ Health Perspect
  doi: 10.1289/ehp.6414
  contributor:
    fullname: Birman-Deych
– volume: 117
  start-page: e546
  year: 2006
  end-page: e556
  ident: CR3
  article-title: Pesticide exposure and stunting as independent predictors of neurobehavioral deficits in Ecuadorian school children
  publication-title: Pediatrics
  doi: 10.1542/peds.2005-1781
  contributor:
    fullname: Debes
– volume: 124
  start-page: 477
  year: 1994
  end-page: 479
  ident: CR10
  article-title: Postmortem drug analysis of meconium in early-gestation human fetuses exposed to cocaine: clinical implications
  publication-title: J Pediatr
  doi: 10.1016/S0022-3476(94)70379-5
  contributor:
    fullname: Knapp
– volume: 117
  start-page: 559
  year: 2009
  end-page: 567
  ident: CR20
  article-title: A biomarker validation study of prenatal chlorpyrifos exposure within an innercity cohort during pregnancy
  publication-title: Environ Health Perspect
  doi: 10.1289/ehp.0800041
  contributor:
    fullname: Hoepner
– volume: 62
  start-page: 623
  year: 2005
  end-page: 629
  ident: CR21
  article-title: Detection of several classes of pesticides and metabolites in meconium by gas chromatography-mass spectrometry
  publication-title: Chromatographia
  doi: 10.1365/s10337-005-0668-7
  contributor:
    fullname: Posecion
– volume: 106
  start-page: 277
  year: 2008
  end-page: 283
  ident: CR11
  article-title: A comparison of infant hair, cord blood and meconium analysis to detect fetal exposure to environmental pesticides
  publication-title: Environ Res
  doi: 10.1016/j.envres.2007.08.014
  contributor:
    fullname: Posecion
– volume: 206
  start-page: 246
  year: 2005
  end-page: 254
  ident: CR19
  article-title: Biomarkers in assessing residential insecticide exposures during pregnancy and effects on fetal growth
  publication-title: Toxicol Appl Pharmacol
  doi: 10.1016/j.taap.2004.11.027
  contributor:
    fullname: Perera
– volume: 26
  start-page: 199
  year: 2005
  end-page: 209
  ident: CR7
  article-title: Association between in utero organophosphate pesticide exposure and abnormal reflexes in neonates
  publication-title: Neurotoxicology
  doi: 10.1016/j.neuro.2004.10.004
  contributor:
    fullname: Gladstone
– volume: 175
  start-page: 1182
  year: 2012
  end-page: 1190
  ident: CR17
  article-title: Association of environmental insecticide exposure and fetal growth with a Bayesian model including multiple exposure sources: the PELAGIE mother-child cohort
  publication-title: Am J Epidemiol
  doi: 10.1093/aje/kwr422
  contributor:
    fullname: Richardson
– volume: 39
  start-page: 364
  year: 2009
  end-page: 373
  ident: CR12
  article-title: Dialkyl phosphates in meconium as a biomarker of prenatal exposure to organophosphate pesticides: a study on pregnant women of rural areas in Crete, Greece
  publication-title: Xenobiotica
  doi: 10.1080/00498250902745090
  contributor:
    fullname: Koutroulakis
– volume: 104
  start-page: 473
  year: 1989
  end-page: 477
  ident: CR15
  article-title: Self-reported exposure to pesticides and radiation related to pregnancy outcome: results from National Natality and Fetal Mortality Surveys
  publication-title: Public Health Rep
  contributor:
    fullname: Kleckner
– volume: 165
  start-page: 717
  year: 2006
  end-page: 725
  ident: CR14
  article-title: Identification of newborns with fetal growth restriction (FGR) in weight and/or length based on constitutional growth potential
  publication-title: Eur J Pediatr
  doi: 10.1007/s00431-005-0045-4
  contributor:
    fullname: Rivière
– volume: 124
  start-page: 477
  year: 1994
  ident: 277_CR10
  publication-title: J Pediatr
  doi: 10.1016/S0022-3476(94)70379-5
  contributor:
    fullname: EM Ostrea Jr
– volume: 106
  start-page: 277
  year: 2008
  ident: 277_CR11
  publication-title: Environ Res
  doi: 10.1016/j.envres.2007.08.014
  contributor:
    fullname: EM Ostrea Jr
– volume: 62
  start-page: 623
  year: 2005
  ident: 277_CR21
  publication-title: Chromatographia
  doi: 10.1365/s10337-005-0668-7
  contributor:
    fullname: D Bielawski
– volume: 39
  start-page: 364
  year: 2009
  ident: 277_CR12
  publication-title: Xenobiotica
  doi: 10.1080/00498250902745090
  contributor:
    fullname: AM Tsatsakis
– volume: 112
  start-page: 388
  year: 2004
  ident: 277_CR18
  publication-title: Environ Health Perspect
  doi: 10.1289/ehp.6414
  contributor:
    fullname: GS Berkowitz
– volume: 104
  start-page: 473
  year: 1989
  ident: 277_CR15
  publication-title: Public Health Rep
  contributor:
    fullname: DA Savitz
– volume: 21
  start-page: 121
  year: 2008
  ident: 277_CR8
  publication-title: Int J Occup Med Environ Health
  doi: 10.2478/v10001-008-0014-z
  contributor:
    fullname: J Jurewicz
– volume: 94
  start-page: 213
  year: 1998
  ident: 277_CR5
  publication-title: Behav Brain Res
  doi: 10.1016/S0166-4328(97)00181-2
  contributor:
    fullname: E Holene
– volume: 10
  start-page: 79
  year: 2011
  ident: 277_CR16
  publication-title: Environ Health
  doi: 10.1186/1476-069X-10-79
  contributor:
    fullname: C Wohlfahrt-Veje
– volume: 84
  start-page: 731
  year: 1994
  ident: 277_CR1
  publication-title: Am J Public Health
  doi: 10.2105/AJPH.84.5.731
  contributor:
    fullname: K Steenland
– volume: 206
  start-page: 246
  year: 2005
  ident: 277_CR19
  publication-title: Toxicol Appl Pharmacol
  doi: 10.1016/j.taap.2004.11.027
  contributor:
    fullname: RM Whyatt
– volume: 165
  start-page: 717
  year: 2006
  ident: 277_CR14
  publication-title: Eur J Pediatr
  doi: 10.1007/s00431-005-0045-4
  contributor:
    fullname: N Mamelle
– volume: 113
  start-page: 1092
  year: 2005
  ident: 277_CR2
  publication-title: Environ Health Perspect
  doi: 10.1289/ehp.7769
  contributor:
    fullname: A Bradman
– volume: 117
  start-page: e546
  year: 2006
  ident: 277_CR3
  publication-title: Pediatrics
  doi: 10.1542/peds.2005-1781
  contributor:
    fullname: P Grandjean
– volume: 26
  start-page: 199
  year: 2005
  ident: 277_CR7
  publication-title: Neurotoxicology
  doi: 10.1016/j.neuro.2004.10.004
  contributor:
    fullname: JG Young
– volume: 175
  start-page: 1182
  year: 2012
  ident: 277_CR17
  publication-title: Am J Epidemiol
  doi: 10.1093/aje/kwr422
  contributor:
    fullname: C Petit
– volume-title: Environ Res
  year: 2013
  ident: 277_CR13
  contributor:
    fullname: T Berton
– volume: 20
  start-page: 624
  year: 1978
  ident: 277_CR6
  publication-title: Bull Environ Contam Toxicol
  doi: 10.1007/BF01683575
  contributor:
    fullname: L Rosenstein
– volume: 19
  start-page: 851
  year: 2008
  ident: 277_CR4
  publication-title: Epidemiology
  doi: 10.1097/EDE.0b013e318187cc5d
  contributor:
    fullname: AJ Handal
– volume: 117
  start-page: 559
  year: 2009
  ident: 277_CR20
  publication-title: Environ Health Perspect
  doi: 10.1289/ehp.0800041
  contributor:
    fullname: RM Whyatt
– volume: 51
  start-page: 60
  year: 2002
  ident: 277_CR9
  publication-title: Ecotoxicol Environ Saf
  doi: 10.1006/eesa.2001.2110
  contributor:
    fullname: Z Hong
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Snippet Résumé Objectif L’étude MecoExpo menée en Picardie, région agricole utilisatrice de pesticides, visait à mettre en relation l’exposition parentale et...
The MecoExpo study was conducted in Picardy, an agricultural region where pesticides are used. This study was designed to evaluate the relationship between...
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SubjectTerms Article Original
Critical Care Medicine
Divers
Environmental Sciences
Generalites
Imaging
Intensive
Medicine
Medicine & Public Health
Obstetrics/Perinatology/Midwifery
Original Article
Pediatrics
Radiology
Sante publique. Hygiene-medecine du travail
Santé publique. Hygiène
Sciences biologiques et medicales
Sciences medicales
Title Cohorte MecoExpo : utilisation du méconium pour estimer l’exposition in utero aux pesticides des nouveau-nés en Picardie
URI https://link.springer.com/article/10.1007/s12611-014-0277-5
https://ineris.hal.science/ineris-01863946
Volume 6
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