STUDY OF THE USEFULNESS OF SCS-4 (4% SODIUM CITRATE SOLUTION) AS AN ANTICOAGULANT FOR DONOR PLASMAPHERESIS

ACD-A solution, anticoagulant for preserved blood, has been used for donor plasmapheresis (DP), howerver it has some undesirable problems for the puropose. This time, we examined usefulness of SCS-4 (4% sodium citrate solution, USP XXI) as an anticoagulant for DP in 85 healthy volunteers, 75 cases b...

Full description

Saved in:
Bibliographic Details
Published inJournal of the Japan Society of Blood Transfusion Vol. 35; no. 3; pp. 322 - 331
Main Authors Tomono, Tsugikazu, Nakase, Toshie, Yokoyama, Shigeki, Endo, Nobuyuki, Sekiguchi, Sadayoshi, Ogawa, Masaaki, Shiraki, Hiroshi, Ikeda, Hiroyuki
Format Journal Article
LanguageJapanese
Published The Japan Society of Transfusion Medicine and Cell Therapy 1989
Online AccessGet full text
ISSN0546-1448
1883-8383
DOI10.3925/jjtc1958.35.322

Cover

More Information
Summary:ACD-A solution, anticoagulant for preserved blood, has been used for donor plasmapheresis (DP), howerver it has some undesirable problems for the puropose. This time, we examined usefulness of SCS-4 (4% sodium citrate solution, USP XXI) as an anticoagulant for DP in 85 healthy volunteers, 75 cases by membrane method and 10 cases by centrifugal method. SCS-4 was safely used as an anticoagulant for DP in both methods, in less volume than the conventional ACD-A solution because of the higher citrate concentration. The blood picture, biochemistry, coagulation factors and immunoglobulin of the donors returned normal promptly in both methods. We could obtain plasma with high concentration of total protein, albumin, immunoglobulin and coagulation factors. These results indicate that SCS-4 is useful as an anticoagulant for DP.
ISSN:0546-1448
1883-8383
DOI:10.3925/jjtc1958.35.322