A case of pemphigus vulgaris localized in the gingiva

• Published in: Japanese Journal of Oral and Maxillofacial Surgery Vol. 36; no. 9; pp. 2137 - 2141
• Main Authors: UMINO, Satoshi, FUJITA, Kiyohide, KAWABE, Ryoichi, MIYAZAKI, Chika
• Format: Journal Article
• Language: English
• Published: Japanese Society of Oral and Maxillofacial Surgeons 1990
• Subjects: glngiva; pemphigus vulgaris; steroid therapy
• ISSN: 0021-5163; 2186-1579
• DOI: 10.5794/jjoms.36.2137

Pemphigus vulgaris is a chronic erosive and bullous disease of skin and mucous membranes histologically characterized by acantholysis and degeneration of epithelial cells. The authors report a 44-year-old female of pemphigus vulgaris who showed erosion of 2-5 buccal and lingual gingiva as a single lesion. The diagnosis of pemphigus vulgaris in this case was made by clinical evidence of Nikolsky's sign, immunological evidence of positive vulgaris antibody, and laistopathological findings including Tzanck test results. This case had no recurrence for the past 4 years after local injection of steroid hormone and gold therapy. The authors discussed the treatment of pemphigus vulgaris of buccal and lingual gingiva and emphasized the effect of locally injected steroid hormones.