Antimicrobial activity of Imidazolidinyl urea

Antimicrobial activity of Imidazolidinyl urea (IU) is tested in M/10 phosphate buffer solutions against two strains; Escherichia coli and Pseudomonas aeruginosa. The influences of pH, gelatin and collagen hydrolysate on its activity are also tested respectively; the following results are obtained. A...

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Published inJournal of Japan Cosmetic Chemists Association Vol. 9; no. 2; pp. 56 - 61
Main Author Nakano, Eiji
Format Journal Article
LanguageEnglish
Published THE SOCIETY OF COSMETIC CHEMISTS OF JAPAN 1975
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ISSN1884-6572
1884-6572
DOI10.5107/sccj1970.9.2_56

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Abstract Antimicrobial activity of Imidazolidinyl urea (IU) is tested in M/10 phosphate buffer solutions against two strains; Escherichia coli and Pseudomonas aeruginosa. The influences of pH, gelatin and collagen hydrolysate on its activity are also tested respectively; the following results are obtained. Antimicrobial activity of Imidazolidinyl urea (IU) has a tendency to be more effective in alkaline pH range. Imidazolidinyl urea (IU) is slightly inactivated in the presence of gelatin. But its activity is more effectively decreased in collagen hydrolysate solution, especially in the case of Pseudomonas aeruginosa. In this collagen hydrolysate solution, the growth of two microbes is less inhibited in alkaline pH range than in acid one. Weak phototoxity of Imidazolidinyl urea (IU) against Escherichia coli is recognized by irradiation of 290-350nm ray.
AbstractList Antimicrobial activity of Imidazolidinyl urea (IU) is tested in M/10 phosphate buffer solutions against two strains; Escherichia coli and Pseudomonas aeruginosa. The influences of pH, gelatin and collagen hydrolysate on its activity are also tested respectively; the following results are obtained. Antimicrobial activity of Imidazolidinyl urea (IU) has a tendency to be more effective in alkaline pH range. Imidazolidinyl urea (IU) is slightly inactivated in the presence of gelatin. But its activity is more effectively decreased in collagen hydrolysate solution, especially in the case of Pseudomonas aeruginosa. In this collagen hydrolysate solution, the growth of two microbes is less inhibited in alkaline pH range than in acid one. Weak phototoxity of Imidazolidinyl urea (IU) against Escherichia coli is recognized by irradiation of 290-350nm ray.
Author Nakano, Eiji
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References 5) 野田春彦, 蛋白質化学 (4), P. 101 (1956
3) M. G. DeNavarre and H. E. Bailey, J. Soc. Cosm. Chem., 7, 427 (1956
2) 加藤洋次, 高橋明, 田宮久彰, 河野通治, 霜三雄, 食衛誌, 7, 60 (1966
1) P. A. Berke and W. E. Rosen, American Perfumer and Cosmetics, 85, 55 (1970
4) M. D. Ray., K. E. Avis and C. C. Flarigan. Jr, J. Pharm. Sci., 57 [4] 609 (1968
References_xml – reference: 2) 加藤洋次, 高橋明, 田宮久彰, 河野通治, 霜三雄, 食衛誌, 7, 60 (1966)
– reference: 3) M. G. DeNavarre and H. E. Bailey, J. Soc. Cosm. Chem., 7, 427 (1956)
– reference: 4) M. D. Ray., K. E. Avis and C. C. Flarigan. Jr, J. Pharm. Sci., 57 [4] 609 (1968)
– reference: 1) P. A. Berke and W. E. Rosen, American Perfumer and Cosmetics, 85, 55 (1970)
– reference: 5) 野田春彦, 蛋白質化学 (4), P. 101 (1956)
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Title Antimicrobial activity of Imidazolidinyl urea
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