Perspectives of optical coherence tomography imaging and Raman spectroscopy in cancer diagnosis

Biomedical optical imaging and optical spectroscopy are rapidly emerging as strong contenders for non-invasive optical biopsy. In biomedical imaging, Optical Coherence Tomography (OCT) is an established imaging modality for non-contact depth-resolved three-dimensional imaging with micrometer scale r...

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Bibliographic Details
Published inBiomedical spectroscopy and imaging Vol. 4; no. 1; pp. 35 - 55
Main Authors Divakar Rao, K., Sahoo, N.K., Krishna, C. Murali
Format Journal Article
LanguageEnglish
Published 2015
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Summary:Biomedical optical imaging and optical spectroscopy are rapidly emerging as strong contenders for non-invasive optical biopsy. In biomedical imaging, Optical Coherence Tomography (OCT) is an established imaging modality for non-contact depth-resolved three-dimensional imaging with micrometer scale resolution. OCT provides label-free micro-structural morphological information of the tissue. Raman spectroscopy is a complementary tool for obtaining molecular-specific information for diagnosis. This article provides a brief overview of the underlying principles of OCT and Raman spectroscopy, their instrumentation with representative latest developments in cancer diagnosis.
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ISSN:2212-8794
DOI:10.3233/BSI-140097