Cytogenetic analysis of acute myeloid leukemia with t(8;21): Its clinical correlation with loss of X Chromosome and Del (9q)

• Published in: Journal of Applied Hematology Vol. 9; no. 2; pp. 51 - 58
• Main Authors: Abd El Ghafar, AfafAbd El Aziz, El-Sakhawy, YasminNabil, Safwat, NesmaAhmed, Ismail, HebaMohamed
• Format: Journal Article
• Language: English
• Published: Wolters Kluwer Medknow Publications 2018
• Subjects: Acute myeloid leukemia; del 9q; loss of X chromosome; t(8;21)

BACKGROUND: Translocation (8;21), t(8;21), is one of the most common cytogenetic abnormalities in adult de novo acute myeloid leukemia (AML) patients. It is usually associated with secondary chromosomal abnormalities; however, it's unclear whether these abnormalities affect the clinical charact...