EFFICIENT APPROACH TOWARDS THE POLYSUBSTITUTED 4H-PYRAN HYBRID QUINOLONE DERIVATIVES AND SUBSEQUENT COPPER-CATALYZED HYDROXYLATION OF HALOARENES

A proficient and feasible approach towards polysubstituted quinolone conjugated 4H-pyrans has been elucidated. The illustrated phenomenon concern with the base-mediated multicomponent reaction and subsequent copper-catalyzed hydroxylation of C-X bond emerging in an amide functionality. The developed...

Full description

Saved in:
Bibliographic Details
Published inHeterocycles Vol. 102; no. 3; pp. 465 - 479
Main Authors Kumar, Vipin, Singh, Dharmender, Gujjarappa, Raghuram, Malakar, Chandi C., Singh, Virender
Format Journal Article
LanguageEnglish
Published OXFORD Elsevier 01.01.2021
Subjects
Chemistry
Chemistry, Organic
Physical Sciences
Science & Technology
C BOND-CLEAVAGE
ENANTIOSELECTIVE SYNTHESIS
ONE-POT SYNTHESIS
ANTIBACTERIAL ACTIVITY
GREEN SYNTHESIS
ARYL HALIDES
HOMOGENEOUS CATALYST
HETEROGENEOUS CATALYST
SIMPLE KETONES
ASSISTED MULTICOMPONENT SYNTHESIS
Online AccessGet more information

Cover

More Information
Summary:A proficient and feasible approach towards polysubstituted quinolone conjugated 4H-pyrans has been elucidated. The illustrated phenomenon concern with the base-mediated multicomponent reaction and subsequent copper-catalyzed hydroxylation of C-X bond emerging in an amide functionality. The developed reaction conditions showcased considerable substrate scope and functional group tolerance by giving the desired products in good yields.
ISSN:0385-5414
1881-0942
DOI:10.3987/COM-20-14383