A Case Report of Myxedema Megacolon Required Sigmoidectomy
A 62-year-old male was admitted to the hospital with acute abdominal pain. X-ray films of the abdomen showed ileus due to sigma volvulus, and he underwent a repairing operation. After surgery, myxedematous skin appeared on his extremities, and thyroidal examination revealed the patient had had marke...
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| Published in | Nippon Shokaki Geka Gakkai zasshi Vol. 23; no. 4; pp. 934 - 937 |
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| Main Authors | , , , , |
| Format | Journal Article |
| Language | Japanese |
| Published |
The Japanese Society of Gastroenterological Surgery
1990
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| Subjects | |
| Online Access | Get full text |
| ISSN | 0386-9768 1348-9372 |
| DOI | 10.5833/jjgs.23.934 |
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| Abstract | A 62-year-old male was admitted to the hospital with acute abdominal pain. X-ray films of the abdomen showed ileus due to sigma volvulus, and he underwent a repairing operation. After surgery, myxedematous skin appeared on his extremities, and thyroidal examination revealed the patient had had marked hypothyroidism with myxedema megacolon. For three months after the surgery he received thyroid hormone treatment, but paresis of the large intestine worsened. Accordingly, the sigmoid colon was resected. Histological examination revealed marked deposits of myxedematous material in the submucosa layer and the internal circurating muscles. He was discharged from the hospital and is living well with treatment with levothyroxine sodium. |
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| AbstractList | A 62-year-old male was admitted to the hospital with acute abdominal pain. X-ray films of the abdomen showed ileus due to sigma volvulus, and he underwent a repairing operation. After surgery, myxedematous skin appeared on his extremities, and thyroidal examination revealed the patient had had marked hypothyroidism with myxedema megacolon. For three months after the surgery he received thyroid hormone treatment, but paresis of the large intestine worsened. Accordingly, the sigmoid colon was resected. Histological examination revealed marked deposits of myxedematous material in the submucosa layer and the internal circurating muscles. He was discharged from the hospital and is living well with treatment with levothyroxine sodium. |
| Author | Ozaki, Azusa Iwasaki, Yoji Adachi, Shinya Osada, Akira Watanabe, Muneaki |
| Author_xml | – sequence: 1 fullname: Osada, Akira organization: Department of Surgery, Kinu Medical Associaton Hospital – sequence: 1 fullname: Ozaki, Azusa organization: Department of Surgery, Kinu Medical Associaton Hospital – sequence: 1 fullname: Iwasaki, Yoji organization: Department of Surgery, Institute of Clinical Medicine, University of Tsukuba – sequence: 1 fullname: Adachi, Shinya organization: Department of Surgery, Kinu Medical Associaton Hospital – sequence: 1 fullname: Watanabe, Muneaki organization: Department of Surgery, Kinu Medical Associaton Hospital |
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| References | 4) Hohl RD, Nixon RK: Myxedema ileus. Arch Intern Med 115: 145-150, 1965 6) 松林直, 千福恵子, 高市幸彦ほか: 粘液水腫に併発した偽性腸閉塞症の1例. 内科59: 793-795, 1987 9) Douglass RC, Jacobson SD: Pathologic changes in adult myxedema: Survey of 10 necropsies. J Clin Endocr 17: 1354-1364, 1957 3) Solano FX Jr, Starling RC, Levey GS: Myxedema megacolon. Arch Intern Med 145: 231, 1985 5) Burrell M, Cronan J, Megna D et al: Myxedema megacolon. Gastrointest Radiol 5: 181-186, 1980 11) Duret RL, Bastenie PA: Intestinal disorders in hypothyroidism clinical and manometric study. Dig Dis 16: 723-727, 1971 1) Bastenie PA: Paralytic ileus in severe hypothyroidism. Lancet 1: 413-416, 1946 2) Faulk DL, Anuras S, Christensen J: Chronic intestinal pseudoobstruction Gastroenterology 74: 922-931, 1978 7) 大橋明, 増永義則, 堤卓也ほか: 慢性甲状腺炎に合併したmegacolonの1例. 大分病医誌16: 75-78, 1987 8) 前田純雄, 今井隆弘, 守田則一ほか: 甲状腺機能低下症に合併した巨大結腸症の1例. 日内会誌76: 756-757, 1987 10) Wells I, Smith B, Hinton M: Acute ileus in myxedema. Br Med J 22: 211-212, 1977 |
| References_xml | – reference: 5) Burrell M, Cronan J, Megna D et al: Myxedema megacolon. Gastrointest Radiol 5: 181-186, 1980 – reference: 11) Duret RL, Bastenie PA: Intestinal disorders in hypothyroidism clinical and manometric study. Dig Dis 16: 723-727, 1971 – reference: 1) Bastenie PA: Paralytic ileus in severe hypothyroidism. Lancet 1: 413-416, 1946 – reference: 4) Hohl RD, Nixon RK: Myxedema ileus. Arch Intern Med 115: 145-150, 1965 – reference: 8) 前田純雄, 今井隆弘, 守田則一ほか: 甲状腺機能低下症に合併した巨大結腸症の1例. 日内会誌76: 756-757, 1987 – reference: 3) Solano FX Jr, Starling RC, Levey GS: Myxedema megacolon. Arch Intern Med 145: 231, 1985 – reference: 10) Wells I, Smith B, Hinton M: Acute ileus in myxedema. Br Med J 22: 211-212, 1977 – reference: 7) 大橋明, 増永義則, 堤卓也ほか: 慢性甲状腺炎に合併したmegacolonの1例. 大分病医誌16: 75-78, 1987 – reference: 2) Faulk DL, Anuras S, Christensen J: Chronic intestinal pseudoobstruction Gastroenterology 74: 922-931, 1978 – reference: 6) 松林直, 千福恵子, 高市幸彦ほか: 粘液水腫に併発した偽性腸閉塞症の1例. 内科59: 793-795, 1987 – reference: 9) Douglass RC, Jacobson SD: Pathologic changes in adult myxedema: Survey of 10 necropsies. J Clin Endocr 17: 1354-1364, 1957 |
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| SubjectTerms | hypothyroidism myxedema megacolon paralytic ileus |
| Title | A Case Report of Myxedema Megacolon Required Sigmoidectomy |
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