Importance of Testing for Apnea in the Diagnosis of Brain Death

We tried to evaluate 2 patients both in deep coma and on ventilator, using the Criteria for Brain Death by the Japanese Ministry of Public Welfare. One was a 17 year-old boy with head injury from a traffic accident and the other was a 31 year-old female resuscitated from 20min of cardiac arrest. In...

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Published inNihon Rinshō Masui Gakkai shi Vol. 8; no. 3; pp. 279 - 283
Main Authors ARAI, Tatsuru, HAMAMI, Gen, TABO, Etsuo
Format Journal Article
LanguageEnglish
Published THE JAPAN SOCIETY FOR CLINICAL ANESTHESIA 1988
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ISSN0285-4945
1349-9149
DOI10.2199/jjsca.8.279

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Abstract We tried to evaluate 2 patients both in deep coma and on ventilator, using the Criteria for Brain Death by the Japanese Ministry of Public Welfare. One was a 17 year-old boy with head injury from a traffic accident and the other was a 31 year-old female resuscitated from 20min of cardiac arrest. In the first patient brain death was diagnosed without any problems. In the 2nd patient, during apneic test the PO2 decreased from 330mmHg (FIO2 1.0) to 90mmHg in 2min, so the test had to be discontinued. The rapidity in the decrease of PO2 was, we assume, due to instability of the patinet's respiratory system. This means that everything possible, a prerequisite for the testing of brain death, may not have been carried out. In this paper we discussed the importance of testing for apnea in the diagnosis of brain death in detail.
AbstractList We tried to evaluate 2 patients both in deep coma and on ventilator, using the Criteria for Brain Death by the Japanese Ministry of Public Welfare. One was a 17 year-old boy with head injury from a traffic accident and the other was a 31 year-old female resuscitated from 20min of cardiac arrest. In the first patient brain death was diagnosed without any problems. In the 2nd patient, during apneic test the PO2 decreased from 330mmHg (FIO2 1.0) to 90mmHg in 2min, so the test had to be discontinued. The rapidity in the decrease of PO2 was, we assume, due to instability of the patinet's respiratory system. This means that everything possible, a prerequisite for the testing of brain death, may not have been carried out. In this paper we discussed the importance of testing for apnea in the diagnosis of brain death in detail.
Author HAMAMI, Gen
TABO, Etsuo
ARAI, Tatsuru
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References 1) Pallis C: ABC of brain stem death. The Devonshire Press, Torquay, 1983
4) Frowein R, Hamel E, Michard KE, Haupt W: Extension of the criteria for the diagnosis of brain death. ICRAN, 1986
3) Walker AE (太田富雄訳: 脳死-医学と社会の接点. メディカル•サイエンス•インターナショナル, 東京, 1987, pp. 43～79
2) 武下浩: 脳死. 麻酔 36: 1706～1713, 1987
5) German Surgical Society, Statement by the Commission on Reanimation and Organ Transplantation: Definition of the signs and time of death. German Med Monthly 13: 359, 1968
References_xml – reference: 1) Pallis C: ABC of brain stem death. The Devonshire Press, Torquay, 1983
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– reference: 5) German Surgical Society, Statement by the Commission on Reanimation and Organ Transplantation: Definition of the signs and time of death. German Med Monthly 13: 359, 1968
– reference: 2) 武下浩: 脳死. 麻酔 36: 1706～1713, 1987
– reference: 4) Frowein R, Hamel E, Michard KE, Haupt W: Extension of the criteria for the diagnosis of brain death. ICRAN, 1986
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Title Importance of Testing for Apnea in the Diagnosis of Brain Death
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