Associations between methylmercury, n-3 polyunsaturated fatty acids and antinuclear antibodies in young adults from the Seychelles Child Development Study (SCDS)

• Published in: Proceedings of the Nutrition Society Vol. 79; no. OCE2
• Main Authors: McSorley, Emeir M., Mulhern, Maria S., Yeates, Alison J., Harrington, Donald, van Wijngaarden, Edwin, Thurston, Sally W., Jusko, Todd A., Spence, Toni, Davidson, Philip W., Myres, Gary J., Watson, Gene E., Shamlaye, Conrad F., Strain, J.J.
• Format: Journal Article
• Language: English
• Published: Cambridge, UK Cambridge University Press 2020
• Subjects: Anti-DNA antibodies; Antibodies; Antinuclear antibodies; Autoimmune diseases; autoimmunity; Bioaccumulation; child development; Consumption; Dimethylmercury; Disease control; Exposure; Fatty acids; Fish; fish consumption; humans; Immunoglobulin A; Immunoglobulin G; Immunoglobulin M; Immunoglobulins; inflammation; Markers; Mercury (metal); Methylmercury; methylmercury compounds; omega-3 fatty acids; Polyunsaturated fatty acids; Prenatal experience; Regression analysis; Regression models; Seychelles; Signs and symptoms; waist circumference; Young adults; Seychelles

The association of MeHg exposure through fish consumption on human autoimmunity remains unclear. Fish also contain n-3 long chain polyunsaturated fatty acids (LCPUFA) that are known to regulate inflammation and mitigate autoimmune disease symptoms. We studied the association of low-level exposure to...